2-Methyl-1,4,7,10,13-pentaoxacyclopentadecane

Base Information

• Chemical Name: 2-Methyl-1,4,7,10,13-pentaoxacyclopentadecane
• CAS No.: 68167-84-0
• Molecular Formula: C11H22O5
• Molecular Weight: 234.293
• European Community (EC) Number: 269-013-9
• DSSTox Substance ID: DTXSID10987671
• Nikkaji Number: J317.378J
• Mol file: 68167-84-0.mol

Synonyms:2-Methyl-1,4,7,10,13-pentaoxacyclopentadecane;68167-84-0;EINECS 269-013-9;Methyl-15-crown-5;SCHEMBL4384047;DTXSID10987671

Chemical Property of 2-Methyl-1,4,7,10,13-pentaoxacyclopentadecane

Chemical Property:

• Vapor Pressure: 0.000131mmHg at 25°C
• Boiling Point: 344.5°Cat760mmHg
• Flash Point: 140.1°C
• PSA: 46.15000
• Density: 0.97g/cm³
• LogP: 0.47150
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 234.14672380
• Heavy Atom Count: 16
• Complexity: 153

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1COCCOCCOCCOCCO1

Technology Process of 2-Methyl-1,4,7,10,13-pentaoxacyclopentadecane

There total 3 articles about 2-Methyl-1,4,7,10,13-pentaoxacyclopentadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propylene glycol (57-55-6,63625-56-9) + triethylene glycol di-(p-toluenesulfonate) (19249-03-7) → hydromethyl-15-crown-5 (68167-84-0)

Guidance literature:

With sodium methylate; Multistep reaction; 1.) sodium methoxide, dioxane, diol, 10 min 2.) 1,2-bis<2'-(toluene-p-sulphonyloxy)ethoxy>ethane, dioxane, 5 min, reflux;

Reference yield:

Tetraethylene glycol (112-60-7) + methyloxirane (75-56-9,16033-71-9) → hydromethyl-15-crown-5 (68167-84-0)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo01314a030

Reference yield:

→ hydromethyl-15-crown-5 (68167-84-0)

Guidance literature:

aus Polyether (III), TsCl/NaOH;

DOI:10.1039/C39780000504

upstream raw materials:

propylene glycol

triethylene glycol di-(p-toluenesulfonate)

Tetraethylene glycol

methyloxirane

Refernces

• 1、 Ikeda, Isao,Yamamura, Shingo,Nakatsuji, Yohji,Okahara, Mitsuo. "Synthesis of Substituted Crown Ethers from Oligoethylene Glycols". . p. 5355 - 5358. Retrieved 2007/10/02.