3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol

Base Information

Chemical Name:3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol
CAS No.:73924-72-8
Molecular Formula:C₂₁H₂₆N₂O₃
Molecular Weight:354.449
Hs Code.:
Nikkaji Number:J383.762I

Synonyms:BRN 0047977;3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol;6-Quinuclidinemethanol, 3-ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-;4-23-00-03255 (Beilstein Handbook Reference);73924-72-8;SCHEMBL18961833;Cinchonan-9-ol, 3,10-didehydro-10,11-dihydro-6'-(2-hydroxyethoxy)-, (1.xi.,4.xi.,8.xi.)-;LS-143134;5-Ethylidene-alpha-[6-(2-hydroxyethoxy)-4-quinolinyl]-1-azabicyclo[2.2.2]octane-2-methanol

Suppliers and Price of 3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 1 raw suppliers

Chemical Property of 3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol

Chemical Property:

Boiling Point:571.6°Cat760mmHg
Flash Point:299.5°C
PSA：65.82000
Density:1.27g/cm³
LogP:2.61770
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:354.19434270
Heavy Atom Count:26
Complexity:512

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC=C1CN2CCC1CC2C(C3=C4C=C(C=CC4=NC=C3)OCCO)O
Isomeric SMILES:C/C=C/1\CN2CCC1CC2C(C3=C4C=C(C=CC4=NC=C3)OCCO)O

Technology Process of 3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol

There total 7 articles about 3-Ethylidene-alpha-(6-(2-hydroxyethoxy)-4-quinolyl)-6-quinuclidinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3Z,8S,9R)-6'-(2-benzyloxy-ethoxy)-10,11-dihydro-cinchon-3⁽¹⁰⁾-en-9-ol

: 73924-72-8
(3Z,8S,9R)-6'-(2-hydroxy-ethoxy)-10,11-dihydro-cinchon-3⁽¹⁰⁾-en-9-ol

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja01273a059 DOI:10.1021/ja01246a025

Reference yield:

: Kalium-Salz des Apochinins

: 73924-72-8
(3Z,8S,9R)-6'-(2-hydroxy-ethoxy)-10,11-dihydro-cinchon-3⁽¹⁰⁾-en-9-ol

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol

2: benzyl alcohol

3: aqueous HCl

With hydrogenchloride; ethanol; benzyl alcohol;
DOI:10.1021/ja01273a059

Reference yield:

: (3Z,8S,9R)-6'-(2-chloro-ethoxy)-10,11-dihydro-cinchon-3⁽¹⁰⁾-en-9-ol

: 73924-72-8
(3Z,8S,9R)-6'-(2-hydroxy-ethoxy)-10,11-dihydro-cinchon-3⁽¹⁰⁾-en-9-ol

Guidance literature:: Multi-step reaction with 2 steps

1: benzyl alcohol

2: aqueous HCl

With hydrogenchloride; benzyl alcohol;
DOI:10.1021/ja01273a059