4-Hydroxybutyl methacrylate

Base Information

• Chemical Name: 4-Hydroxybutyl methacrylate
• CAS No.: 997-46-6
• Molecular Formula: C8H14O3
• Molecular Weight: 158.197
• European Community (EC) Number: 213-642-3,684-174-9
• DSSTox Substance ID: DTXSID30244213
• Nikkaji Number: J25.107K
• Wikidata: Q83128517
• Mol file: 997-46-6.mol

Synonyms:4-Hydroxybutyl methacrylate;997-46-6;29008-35-3;4-hydroxybutyl 2-methylprop-2-enoate;EINECS 213-642-3;2-Propenoic acid, 2-methyl-, monoester with 1,2-butanediol;starbld0008704;4-methacryloyloxybutan-1-ol;SCHEMBL14872;DTXSID30244213;AMY18807;Methacrylic acid 4-hydroxybutyl ester;AKOS025296078;FT-0618705;EN300-188466;J-017353

Chemical Property of 4-Hydroxybutyl methacrylate

Chemical Property:

• Vapor Pressure: 0.00845mmHg at 25°C
• Boiling Point: 236.6°Cat760mmHg
• PKA: 14.98±0.10(Predicted)
• Flash Point: 93.5°C
• PSA: 46.53000
• Density: 1.01g/cm³
• LogP: 0.87820
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 158.094294304
• Heavy Atom Count: 11
• Complexity: 140

Purity/Quality:

99%, ^*data from raw suppliers

4-HYDROXYBUTYL METHACRYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)OCCCCO

Technology Process of 4-Hydroxybutyl methacrylate

There total 8 articles about 4-Hydroxybutyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.57%

Butane-1,4-diol (110-63-4) + methacrylic acid methyl ester (80-62-6,114512-63-9,143476-91-9,25188-98-1,9011-14-7) → 4-methacryloyloxybutyl alcohol (997-46-6)

Guidance literature:

With 10H-phenothiazine; sodium N,N-diethyldithiocarbamate; In cyclohexane; at 87 ℃; for 5h; Concentration; Reagent/catalyst;

Reference yield: 93.0%

4-(Vinyloxy)butyl methacrylate (82386-37-6) → 4-methacryloyloxybutyl alcohol (997-46-6)

Guidance literature:

With toluene-4-sulfonic acid; ethylene glycol; at 40 ℃; for 1h; under 225.023 Torr; Reagent/catalyst;

Reference yield: 63.0%

Butane-1,4-diol (110-63-4) + poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) → 4-methacryloyloxybutyl alcohol (997-46-6)

Guidance literature:

With N,N-dimethylamino-pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;

upstream raw materials:

4-(Vinyloxy)butyl methacrylate

Butane-1,4-diol

poly(methacrylic acid)

methacrylic acid methyl ester

Refernces

• 1、 Iehl, Julien,Nierengarten, Jean-Franois. "Sequential copper catalyzed alkyne-azide and thiol-ene click reactions for the multiple functionalization of fullerene hexaadducts". . p. 4160 - 4162. Retrieved 2010.
• 2、 -. "METHOD FOR PRODUCING HYDROXYALKYL(METH)ACRYLIC ACID ESTER". Paragraph 0064; 0067; 0068. . Retrieved 2018/01/11.
• 3、 -. "DENTAL CURABLE COMPOSITION". Paragraph 0192. . Retrieved 2017/11/01.