2-Cyclohexen-1-one, 4,4-bis([1,1'-biphenyl]-4-yl)-

Base Information

• Chemical Name: 2-Cyclohexen-1-one, 4,4-bis([1,1'-biphenyl]-4-yl)-
• CAS No.: 98509-43-4
• Molecular Formula: C30H24O
• Molecular Weight: 400.52
• Mol file: 98509-43-4.mol

Synonyms:

Chemical Property of 2-Cyclohexen-1-one, 4,4-bis([1,1'-biphenyl]-4-yl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Cyclohexen-1-one, 4,4-bis([1,1'-biphenyl]-4-yl)-

There total 9 articles about 2-Cyclohexen-1-one, 4,4-bis([1,1'-biphenyl]-4-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

3,3-dibiphenylylcyclohex-1-ene (98509-42-3) → 4,4-dibiphenylylcyclohex-2-en-1-one (98509-43-4)

Guidance literature:

With dipyridine chromium trioxide; In dichloromethane; for 48h; Ambient temperature;

DOI:10.1021/ja00311a083

Reference yield:

hydroxycyclopentanecarboxylic acid ethyl ester (41248-23-1) → 4,4-dibiphenylylcyclohex-2-en-1-one (98509-43-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 40 percent / n-BuLi / tetrahydrofuran; hexane / 1 h / Ambient temperature

2: 85 percent / I₂ / acetic acid / 0.08 h / Heating

3: 88 percent / cc. HCl / tetrahydrofuran / 20 h / Heating

4: 82 percent / MeLi / diethyl ether; benzene / 1 h / Heating

5: 37 percent / CrO₃*(pyridine)2 / CH₂Cl₂ / 48 h / Ambient temperature

With hydrogenchloride; n-butyllithium; methyllithium; iodine; dipyridine chromium trioxide; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; acetic acid; benzene;

DOI:10.1021/ja00311a083

Reference yield:

dibiphenylyl-1-(1-hydroxy-1-cyclopentyl)carbinol (98509-39-8) → 4,4-dibiphenylylcyclohex-2-en-1-one (98509-43-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / I₂ / acetic acid / 0.08 h / Heating

2: 88 percent / cc. HCl / tetrahydrofuran / 20 h / Heating

3: 82 percent / MeLi / diethyl ether; benzene / 1 h / Heating

4: 37 percent / CrO₃*(pyridine)2 / CH₂Cl₂ / 48 h / Ambient temperature

With hydrogenchloride; methyllithium; iodine; dipyridine chromium trioxide; In tetrahydrofuran; diethyl ether; dichloromethane; acetic acid; benzene;

DOI:10.1021/ja00311a083

upstream raw materials:

cis-5,6-dibiphenylylbicyclo<3.1.0>hexan-2-one

3,3-dibiphenylylcyclohex-1-ene

methyl vinyl ketone

2,2-di(biphenyl-4-yl)acetaldehyde

Downstream raw materials:

trans-5,6-dibiphenylylbicyclo<3.1.0>hexan-2-one

cis-5,6-dibiphenylylbicyclo<3.1.0>hexan-2-one

3,4-dibiphenylylcyclohex-2-en-1-one