ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE
• CAS No.: 41248-23-1
• Molecular Formula: C8H14O3
• Molecular Weight: 158.197
• Hs Code.: 2918199090
• Mol file: 41248-23-1.mol

Synonyms:ethyl 1-hydroxycyclopentane-1-carboxylate;

Chemical Property of ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE

Chemical Property:

• Boiling Point: 206oC
• PKA: 13.28±0.20(Predicted)
• Flash Point: 77oC
• PSA: 46.53000
• Density: 1.144
• LogP: 0.71050
• Storage Temp.: 2-8°C

Purity/Quality:

≥98% ^*data from raw suppliers

Ethyl1-hydroxycyclopentanecarboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 1-hydroxycyclopentanecarboxylate, is a building block used in synthesis of variious compounds such as spiromesifen (S683505), a useful insecticide and miticide in plant breeding. Also useful in cannabis testing kits as a component of pesticide mixes (P698240).

Technology Process of ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE

There total 7 articles about ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-hydroxy-cyclopentanecarboxylic acid (16841-19-3) + ethanol (64-17-5) → hydroxycyclopentanecarboxylic acid ethyl ester (41248-23-1)

Guidance literature:

With sulfuric acid; at 20 ℃; for 72h;

Reference yield: 90.0%

ethanol (64-17-5) + 1-hydroxycyclopentanecarbonitrile (5117-85-1) → hydroxycyclopentanecarboxylic acid ethyl ester (41248-23-1)

Guidance literature:

With hydrogenchloride; In water; at -10 - 25 ℃; for 14h;

Reference yield:

1-hydroxycyclopentanecarbonitrile (5117-85-1) → hydroxycyclopentanecarboxylic acid ethyl ester (41248-23-1)

Guidance literature:

Multi-step reaction with 2 steps

1: conc. HCl / Heating

2: HCl / Heating

With hydrogenchloride;

DOI:10.1016/j.bmcl.2007.06.054

upstream raw materials:

1-hydroxy-cyclopentanecarboxylic acid

ethanol

1-hydroxycyclopentanecarbonitrile

cyclopentanone

Downstream raw materials:

1-[2-(2,4,6-Trimethyl-phenyl)-acetoxy]-cyclopentanecarboxylic acid ethyl ester

cyclopentanespiro-5'-oxazolidine-2',4'-dione

2,2-diphenylcyclohexanone

1-(diphenylhydroxymethyl)-1-hydrohycyclopentane