2-Pyridineacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-

Base Information

Chemical Name:2-Pyridineacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-
CAS No.:99132-31-7
Molecular Formula:C18H21N3
Molecular Weight:279.37900
Hs Code.:

Synonyms:4-(N,N-dimethylamino)-2-phenyl-2-(pyridin-2-yl)-valeronitrile;4-Dimethylamino-2-phenyl-2-pyridin-2-yl-pentanenitrile;4-(N,N-dimethylamino)-2-phenyl-2-(2-pyridyl)-valeronitrile;

Suppliers and Price of 2-Pyridineacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Pyridineacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-

Chemical Property:

Boiling Point:411.2±45.0 °C(Predicted)
PSA：39.92000
Density:1.062±0.06 g/cm3(Predicted)
LogP:3.23148

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyridineacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl-

There total 2 articles about 2-Pyridineacetonitrile, a-[2-(dimethylamino)propyl]-a-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5005-36-7
phenyl-pyridin-2-yl-acetonitrile

: 99132-31-7
4-(dimethylamino)-2-phenyl-2-(2-pyridyl)pentanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) KOH / 1.) DMSO, RT, 50 min, 2.) DMSO, RT 2 h

2: 1.) titanium tetrachloride, 2.) NaBH₄ / 1.) CH₂Cl₂, 5 deg C, 0.5 h, 2.) CH₂Cl₂, MeOH, from 10 deg C to RT, 50 min

With potassium hydroxide; sodium tetrahydroborate; titanium tetrachloride;
DOI:10.1021/jm00035a019

Reference yield:

: 124-40-3
dimethyl amine

: 101509-01-7
4-oxo-2-phenyl-2-(2-pyridyl)pentanenitrile

: 99132-31-7
4-(dimethylamino)-2-phenyl-2-(2-pyridyl)pentanenitrile

Guidance literature:: With sodium tetrahydroborate; titanium tetrachloride; Yield given. Multistep reaction; 1.) CH₂Cl₂, 5 deg C, 0.5 h, 2.) CH₂Cl₂, MeOH, from 10 deg C to RT, 50 min;
DOI:10.1021/jm00035a019