Diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:Diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:35929-79-4
Molecular Formula:C19H22ClNO4
Molecular Weight:363.841
Hs Code.:
European Community (EC) Number:636-841-0
NSC Number:143346
DSSTox Substance ID:DTXSID80957341
Nikkaji Number:J1.036.877D
ChEMBL ID:CHEMBL1825006
Mol file:35929-79-4.mol

Synonyms:diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;35929-79-4;CHEMBL1825006;3,5-diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;NSC143346;Oprea1_170773;Oprea1_600666;SCHEMBL3030945;DTXSID80957341;TXVRICWGWBIUAG-UHFFFAOYSA-N;BDBM50074016;STK387357;AKOS000296841;NSC-143346;NCI60_000953;CS-0298836;EU-0068543;VU0120417-2;EN300-18303962;SR-01000403185;SR-01000403185-1;Z57724605;F0265-0656;diethyl 4-(4-chlorophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate;diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate

Suppliers and Price of Diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIETHYL-4-(PARA-CHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINE DICARBOXYLATE 95.00%
5MG
$ 505.36

Total 4 raw suppliers

Chemical Property of Diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

Vapor Pressure:4.39E-09mmHg at 25°C
Boiling Point:472.1°C at 760 mmHg
Flash Point:239.3°C
PSA：64.63000
Density:1.191g/cm³
LogP:4.02980
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:363.1237359
Heavy Atom Count:25
Complexity:548

Purity/Quality:

97% ^*data from raw suppliers

DIETHYL-4-(PARA-CHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINE DICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=C(C1C2=CC=C(C=C2)Cl)C(=O)OCC)C)C

Technology Process of Diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

There total 16 articles about Diethyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 141-97-9
ethyl acetoacetate

: 104-88-1
4-chlorobenzaldehyde

: 35929-79-4
4-(4-chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With ammonium acetate; at 90 ℃; for 1.03333h; Neat (no solvent);
DOI:10.1002/adsc.201100352

Reference yield: 95.0%

: 141-97-9
ethyl acetoacetate

: 873-76-7
para-Chlorobenzyl alcohol

: 35929-79-4
4-(4-chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With ammonium hydroxide; hydrogen bromide; dimethyl sulfoxide; In water; at 75 ℃; for 2.53333h;
DOI:10.1016/j.tetlet.2018.10.010

Reference yield: 92.0%

: 631-61-8,92206-38-7
ammonium acetate

: 141-97-9
ethyl acetoacetate

: 104-88-1
4-chlorobenzaldehyde

: 35929-79-4
4-(4-chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With Ni(II)-schiff base complex grafted in mesoporous silica MCM-41; In water; at 80 ℃; for 5h; Reagent/catalyst; Solvent; Temperature;
DOI:10.1039/c6ra09371j