N,N-Dipropyl-2-aminotetralin

Base Information

Chemical Name:N,N-Dipropyl-2-aminotetralin
CAS No.:23853-59-0
Molecular Formula:C₁₆H₂₅N
Molecular Weight:231.381
Hs Code.:2921450090
DSSTox Substance ID:DTXSID20946658
Nikkaji Number:J23.568G
Pharos Ligand ID:CMRCN6J4GAK2
ChEMBL ID:CHEMBL284820
Mol file:23853-59-0.mol

Synonyms:2-(di-n-propylamino)tetralin;N,N-dipropyl-2-amino-1,2,3,4-tetrahydronaphthalene;N,N-dipropyl-2-aminotetralin;N,N-dipropyl-2-aminotetralin hydrobromide;N,N-dipropyl-2-aminotetralin hydrochloride;N,N-dipropyl-2-aminotetralin hydrochloride, (R)-isomer;N,N-dipropyl-2-aminotetralin, (+-)-isomer;TL 68;TL-68

Suppliers and Price of N,N-Dipropyl-2-aminotetralin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N,N-Dipropyl-2-aminotetralin

Chemical Property:

Vapor Pressure:0.000148mmHg at 25°C
Boiling Point:332.2°Cat760mmHg
Flash Point:140.4°C
PSA：3.24000
Density:0.95g/cm³
LogP:3.66590
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:231.198699802
Heavy Atom Count:17
Complexity:208

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(CCC)C1CCC2=CC=CC=C2C1

Technology Process of N,N-Dipropyl-2-aminotetralin

There total 8 articles about N,N-Dipropyl-2-aminotetralin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 134394-05-1
(+/-)-2-(dipropylaminoZ)-8-<(trifluoromethylsulfonyl)oxy>tetralin

: 23853-59-0
N,N-dipropyl-2-aminotetralin

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; formic acid; triethylamine; In N,N-dimethyl-formamide; at 60 ℃; for 12h;
DOI:10.1021/jm00078a012

Reference yield:

: 78950-78-4
8-hydroxy-2-(di-N-propylamino)tetralin

: 23853-59-0
N,N-dipropyl-2-aminotetralin

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / CH₂Cl₂ / -78 - 0 °C

2: Et₃N, Pd(OAc)2, formic acid, 1,1'-bis(diphenylphosphino)ferrocene / dimethylformamide / 12 h / 60 °C

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; formic acid; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00078a012