8-OH-Dpat

Base Information

Chemical Name:8-OH-Dpat
CAS No.:78950-78-4
Deprecated CAS:80300-08-9,105558-30-3,122341-76-8,142272-99-9
Molecular Formula:C₁₆H₂₅NO
Molecular Weight:247.381
Hs Code.:
UNII:IWS1724PX6
DSSTox Substance ID:DTXSID30897384
Nikkaji Number:J353.760I,J247.110H
Wikipedia:8-OH-DPAT
Wikidata:Q4644282
Pharos Ligand ID:BNYCRXHKUR76
Metabolomics Workbench ID:66392
ChEMBL ID:CHEMBL56
Mol file:78950-78-4.mol

Synonyms:8-Hydroxy-2-(di-n-propylamino)tetralin;8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide;8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (+-)-Isomer;8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (R)-Isomer,;8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide, (S)-Isomer,;8-Hydroxy-2-(di-n-propylamino)tetralin Hydrochloride, (R)-Isomer,;8-Hydroxy-2-(di-n-propylamino)tetralin Hydrochloride, (S)-Isomer;8-Hydroxy-2-(di-n-propylamino)tetralin, (+-)-Isomer;8-Hydroxy-2-(di-n-propylamino)tetralin, (R)-Isomer;8-Hydroxy-2-(di-n-propylamino)tetralin, (S)-Isomer;8-OH-DPAT

Suppliers and Price of 8-OH-Dpat

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-OH-DPAT
100mg
$ 1200.00

Sigma-Aldrich
S(?)-8-Hydroxy-DPAT hydrobromide solid
5mg
$ 117.00

Sigma-Aldrich
S(?)-8-Hydroxy-DPAT hydrobromide solid
25mg
$ 388.00

Sigma-Aldrich
S(?)-8-Hydroxy-DPAT hydrobromide solid
100mg
$ 1300.00

Medical Isotopes, Inc.
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-olhydrobromide 97%
10 g
$ 1900.00

DC Chemicals
8-OH-DPAT >98%
100 mg
$ 450.00

ChemScene
8-OH-DPAT ≥98.0%
50mg
$ 220.00

ChemScene
8-OH-DPAT ≥98.0%
25mg
$ 140.00

ChemScene
8-OH-DPAT ≥98.0%
10mg
$ 70.00

ChemScene
8-OH-DPAT ≥98.0%
5mg
$ 50.00

Total 20 raw suppliers

Chemical Property of 8-OH-Dpat

Chemical Property:

Vapor Pressure:4.46E-06mmHg at 25°C
Boiling Point:372.5°C at 760 mmHg
Flash Point:168.2°C
PSA：23.47000
LogP:3.37150
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:247.193614421
Heavy Atom Count:18
Complexity:237

Purity/Quality:

≥99% ^*data from raw suppliers

8-OH-DPAT ^*data from reagent suppliers

Safty Information:

Pictogram(s): A poison.
Hazard Codes:A poison.
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O
Uses 8-OH-DPAT, is a potent and selective 5-HT agonist.

Technology Process of 8-OH-Dpat

There total 4 articles about 8-OH-Dpat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 81185-05-9
8-OMethoxy-DPAT hydrochloride

: 78950-78-4
8-hydroxy-2-(di-N-propylamino)tetralin

Guidance literature:: With hydrogen bromide;
DOI:10.1021/jm00140a002

Reference yield:

: 3897-94-7
8-methoxy-2-(di-n-propylamino)tetralin

: 78950-78-4
8-hydroxy-2-(di-N-propylamino)tetralin

Guidance literature:: With hydrogen bromide; at 100 ℃; for 3h;
DOI:10.1016/0223-5234(89)90160-8

Reference yield:

: 5309-19-3
8-methoxy-2-tetralone

: 78950-78-4
8-hydroxy-2-(di-N-propylamino)tetralin

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) p-CH₃-C₆H₄-SO₃H; 2.) H₂, MeSO₃H / 2.) PtO₂ / 2.) ethanol

2: 48percent HBr / 3 h / 100 °C

With methanesulfonic acid; hydrogen bromide; hydrogen; toluene-4-sulfonic acid; platinum(IV) oxide;
DOI:10.1016/0223-5234(89)90160-8