6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-

Base Information

Chemical Name:6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-
CAS No.:1262406-08-5
Molecular Formula:C₁₄H₇F₆N₃O
Molecular Weight:347.219
Hs Code.:
Mol file:1262406-08-5.mol

Synonyms:4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrazolo[3,4-b]pyridin-6-one;6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoroMethyl)-3-[3-(trifluoroMethyl)phenyl]-

Suppliers and Price of 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,7-DIHYDRO-4-(TRIFLUOROMETHYL)-3-[3-(TRIFLUOROMETHYL)PHENYL]-6H-PYRAZOLO-[3,4-B]PYRIDIN-6-ONE 95.00%
5MG
$ 502.54

Total 2 raw suppliers

Chemical Property of 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-

Chemical Property:

PSA：61.80000
LogP:4.36810

Purity/Quality:

99% ^*data from raw suppliers

1,7-DIHYDRO-4-(TRIFLUOROMETHYL)-3-[3-(TRIFLUOROMETHYL)PHENYL]-6H-PYRAZOLO-[3,4-B]PYRIDIN-6-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-

There total 2 articles about 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,7-dihydro-4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 209224-91-9
3-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-amine

: 372-31-6
ethyl 4,4,4-trifluoroacetoacetate

: 1262406-08-5
4-(trifluoromethyl)-3-(3-(trifluoromethyl)phenyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one

Guidance literature:: With acetic acid; for 19h; Reflux;
DOI:10.1371/journal.pone.0184627

Reference yield:

: 27328-86-5
3-trifluoromethylbenzoylacetonitrile

: 1262406-08-5
4-(trifluoromethyl)-3-(3-(trifluoromethyl)phenyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / ethanol / 22 h / 20 °C / Reflux

2: acetic acid / 19 h / Reflux

With acetic acid; hydrazine; In ethanol;
DOI:10.1371/journal.pone.0184627