2-Quinoxalinecarboxamide, N-((1S,2S,4R)-4-(aminocarbonyl)-1-((3-fluorophenyl)methyl)-2,7-dihydroxy-7-methyloctyl)-

Base Information

Chemical Name:2-Quinoxalinecarboxamide, N-((1S,2S,4R)-4-(aminocarbonyl)-1-((3-fluorophenyl)methyl)-2,7-dihydroxy-7-methyloctyl)-
CAS No.:212790-31-3
Molecular Formula:C26H31FN4O4
Molecular Weight:482.555
Hs Code.:
UNII:X3TDA066ME
DSSTox Substance ID:DTXSID00175540
Nikkaji Number:J1.962.139A
Wikidata:Q27076895
Pharos Ligand ID:R6MJQPR5GKB3
ChEMBL ID:CHEMBL1628706
Mol file:212790-31-3.mol

Synonyms:CP 481,715;CP 481715;CP-481,715;CP-481715;CP481,715;CP481715;quinoxaline-2-carboxylic acid (4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyloctyl)amide

Suppliers and Price of 2-Quinoxalinecarboxamide, N-((1S,2S,4R)-4-(aminocarbonyl)-1-((3-fluorophenyl)methyl)-2,7-dihydroxy-7-methyloctyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of 2-Quinoxalinecarboxamide, N-((1S,2S,4R)-4-(aminocarbonyl)-1-((3-fluorophenyl)methyl)-2,7-dihydroxy-7-methyloctyl)-

Chemical Property:

Boiling Point:808.2 °C at 760 mmHg
Flash Point:442.6 °C
Density:1.278 g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:482.23293364
Heavy Atom Count:35
Complexity:709

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(CCC(CC(C(CC1=CC(=CC=C1)F)NC(=O)C2=NC3=CC=CC=C3N=C2)O)C(=O)N)O
Isomeric SMILES:CC(C)(CC[C@H](C[C@@H]([C@H](CC1=CC(=CC=C1)F)NC(=O)C2=NC3=CC=CC=C3N=C2)O)C(=O)N)O
Recent ClinicalTrials:CP-481,715 Nickel Allergy Study.

Technology Process of 2-Quinoxalinecarboxamide, N-((1S,2S,4R)-4-(aminocarbonyl)-1-((3-fluorophenyl)methyl)-2,7-dihydroxy-7-methyloctyl)-

There total 12 articles about 2-Quinoxalinecarboxamide, N-((1S,2S,4R)-4-(aminocarbonyl)-1-((3-fluorophenyl)methyl)-2,7-dihydroxy-7-methyloctyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.2%

: (3R,5S)-5-(((S)-1-amino-2-(3-fluorophenyl)ethyl)dihydro-3-(3-hydroxy-3-methylbutyl)furan-2(3H)one) p-toluenesulfonic acid

: 879-65-2
quinoxaline-2-carboxylic acid

: 212790-31-3
CP 481715

Guidance literature:: quinoxaline-2-carboxylic acid; With 1,1'-carbonyldiimidazole; In ethyl acetate; at 20 - 60 ℃; for 2h; Large scale;

(3R,5S)-5-(((S)-1-amino-2-(3-fluorophenyl)ethyl)dihydro-3-(3-hydroxy-3-methylbutyl)furan-2(3H)one) p-toluenesulfonic acid; With triethylamine; In ethyl acetate; at 20 ℃; for 4h; Large scale;
DOI:10.1021/op050059w