AL-Lad

Base Information

Chemical Name:AL-Lad
CAS No.:65527-61-9
Molecular Formula:C22H27N3O
Molecular Weight:349.476
Hs Code.:
UNII:020O2SR91L
ChEMBL ID:CHEMBL281787
DSSTox Substance ID:DTXSID30215822
Nikkaji Number:J656.984F
Wikidata:Q4652233
Wikipedia:AL-LAD

Synonyms:AL-LAD;65527-61-9;6-allyl-6-nor-LSD;UNII-020O2SR91L;N-Allylnorlysergic Acid N,N-Diethylamide;020O2SR91L;6-Allyl-6-nor-lysergic acid diethylamide;AL-LAD (solution);(6aR,9R)-7-allyl-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide;N-ALLYLNORLSD;CHEMBL281787;SCHEMBL20970937;DTXSID30215822;Q4652233;ERGOLINE-8-CARBOXAMIDE, 9,10-DIDEHYDRO-N,N-DIETHYL-6-(2-PROPENYL)-, (8.BETA.)-;(6aR,9R)-N,N-diethyl-7-prop-2-enyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

Suppliers and Price of AL-Lad

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-AllylnorlysergicAcidN,N-Diethylamide
10mg
$ 1760.00

Total 92 raw suppliers

Chemical Property of AL-Lad

Chemical Property:

Appearance/Colour:Pale Brown Solid
Melting Point:>75°C (dec.)
Boiling Point:558.2±50.0 °C(Predicted)
PKA:17.31±0.40(Predicted)
PSA：39.34000
Density:1.18±0.1 g/cm3 (20 oC 760 Torr)
LogP:3.40010
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:349.215412493
Heavy Atom Count:26
Complexity:582

Purity/Quality:

99%, ^*data from raw suppliers

N-AllylnorlysergicAcidN,N-Diethylamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)CC=C
Isomeric SMILES:CCN(CC)C(=O)[C@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)CC=C
Uses N-Allylnorylsergic Acid N,N-Diethylamide acts as a D1 dopamine receptor antagonist due to its analagous structure to LSD.

Technology Process of AL-Lad

There total 5 articles about AL-Lad which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 106-95-6
allyl bromide

: 35779-43-2
8β-6-norlysergic acid diethylamide

: 65527-61-9
N-AllylnorLSD

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 0.5h;
DOI:10.1021/jm00147a022

Reference yield:

: 35779-41-0
9,10-didehydro-N,N-diethyl-6-cyanoergoline-8β-carboxamide

: 65527-61-9
N-AllylnorLSD

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / Zn / acetic acid; H₂O / 4 h / Heating

2: 88 percent / K₂CO₃ / dimethylformamide / 0.5 h / 25 °C

With potassium carbonate; zinc; In water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00147a022

Reference yield:

: 50-37-3
lysergide

: 65527-61-9
N-AllylnorLSD

Guidance literature:: Multi-step reaction with 3 steps

1: 71 percent / CCl₄; CHCl₃ / 6 h / Heating

2: 61 percent / Zn / acetic acid; H₂O / 4 h / Heating

3: 88 percent / K₂CO₃ / dimethylformamide / 0.5 h / 25 °C

With potassium carbonate; zinc; In tetrachloromethane; chloroform; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00147a022