35779-43-2

Basic information

• Product Name: 6-NORLYSERGIC ACID DIETHYLAMIDE
• Synonyms: 6-NORLYSERGIC ACID DIETHYLAMIDE;n-demethyllysergicaciddiethylamide;NOR-LSD AND NOR-ISO-LSD;Norlysergic Acid DiethylaMide;Ergoline-8-carboxaMide,9,10-didehydro-N,N-diethyl-, (8b)-;(6aR,9R)-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
• CAS NO: 35779-43-2
• Molecular Formula: C₁₉H₂₃N₃O
• Molecular Weight: 309.41
• Product Categories: AlkaloidsNeurobiology;Ergot AlkaloidsDrugs of Abuse;Chemical Structure;Drugs of Abuse;Drugs&Metabolites;ErgotamineForensic and Veterinary Standards;Neat Compounds;Pharmacologicals
• Mol File: 35779-43-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 550 °C at 760 mmHg
• Flash Point: 286.4 °C
• Appearance: orange-tan/powder
• Density: 1.23 g/cm³
• Vapor Pressure: 3.81E-12mmHg at 25°C
• Refractive Index: 1.657
• Storage Temp.: −20°C
• Solubility: alcohol: soluble
• CAS DataBase Reference: 6-NORLYSERGIC ACID DIETHYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-NORLYSERGIC ACID DIETHYLAMIDE(35779-43-2)
• EPA Substance Registry System: 6-NORLYSERGIC ACID DIETHYLAMIDE(35779-43-2)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 36/37/39-45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 35779-43-2(Hazardous Substances Data)

Usage

General Description

6-NORLYSERGIC ACID DIETHYLAMIDE, also known as 6-nor-lysergic acid diethylamide, is a psychoactive substance that is structurally related to LSD. It is a chemical analog of LSD and has been identified as a partial agonist at the 5-HT2A receptor, which is a serotonin receptor that is believed to play a key role in the psychedelic effects of LSD. 6-NORLYSERGIC ACID DIETHYLAMIDE has been studied for its potential use in the treatment of various mental health conditions, including depression and anxiety. Its psychoactive effects are reportedly milder than those of LSD, and it is considered to have a lower potential for abuse. However, it is still classified as a controlled substance in many countries due to its psychoactive properties.

InChI:InChI=1/C19H23N3O/c1-3-22(4-2)19(23)13-8-15-14-6-5-7-16-18(14)12(10-20-16)9-17(15)21-11-13/h5-8,10,13,17,20-21H,3-4,9,11H2,1-2H3/t13-,17-/m1/s1

Upstream product

• 50-37-3 lysergide 
• 35779-41-0 9,10-didehydro-N,N-diethyl-6-cyanoergoline-8β-carboxamide 

Downstream Products

• 65527-61-9 N-AllylnorLSD 
• 50-37-3 lysergide 
• 1198111-11-3 C₂₆H₂₇N₃O₃ 
• 96930-88-0 (6aR,9R)-7-Phenethyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide 
• 65527-63-1 N-PropylnorLSD 
• 65527-62-0 N⁶-Ethyl-norlysergic acid diethylamide 

Relevant articles and documents

Synthetic LSD metabolite for preparing haptens used in an LSD metabolite immunoassay

A general method for the synthesis of OH-LSD and its analogs has been successfully developed. This method is convenient and efficient and allows preparation of a series of OH-LSD analogs with linkers attached at various (C-8, N-6 or N-1) positions.

Stereochemical and NMR Reassignment of 6-Norlysergic Acid Diethylamide and 6-Nor-6-allyllysergic Acid Diethylamide

Conditions are described for the preparation of a salt of 8β-norlysergic acid diethylamide (8β-nor-LSD) 1 as a single epimer from cyanamide 3, whereas earlier preparations gave mixtures of 1 with the 8α epimer 4 in variable proportions: the earlier NMR assignment of 1 is amended and the N(6) alkylation of 1 and 4 with allyl bromide is discussed.