Lysergide

Base Information Edit

Chemical Name:Lysergide
CAS No.:50-37-3
Molecular Formula:C20H25N3O
Molecular Weight:323.438
Hs Code.:
European Community (EC) Number:200-033-2
UN Number:2811
UNII:8NA5SWF92O
DSSTox Substance ID:DTXSID1023231
Nikkaji Number:J9.239H
Wikipedia:Lysergic_acid_diethylamide
Wikidata:Q23118
NCI Thesaurus Code:C76104
Pharos Ligand ID:FYGMUUXA4ARR
Metabolomics Workbench ID:53273
ChEMBL ID:CHEMBL263881
Mol file:50-37-3.mol

Synonyms:Acid Diethylamide, Lysergic;Diethylamide, Lysergic Acid;LSD;LSD 25;LSD-25;Lysergic Acid Diethylamide;Lysergic Acid Diethylamide Tartrate;Lysergide

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Lysergide Edit

Chemical Property:

Appearance/Colour:crystalline solid
Vapor Pressure:8.82E-12mmHg at 25°C
Melting Point:80 - 85 C
Refractive Index:1.651
Boiling Point:541.279 °C at 760 mmHg
PKA:pKa 7.5 (Uncertain)
Flash Point:281.156 °C
PSA：39.34000
Density:1.216 g/cm³
LogP:2.84390
Storage Temp.:−20°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (S
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:323.199762429
Heavy Atom Count:24
Complexity:527
Transport DOT Label:Poison

Purity/Quality:

Safty Information:

Pictogram(s): T+， T， F
Hazard Codes:T+,T,F,Xn
Statements: 26/27/28-40-36/38-23/25-36-20/21/22-11
Safety Statements: 22-28-36-45-33-24-16-7-36/37-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCN(CC)C(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Isomeric SMILES:CCN(CC)C(=O)[C@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
Recent ClinicalTrials:Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety
Recent EU Clinical Trials:Safety and efficacy of repeated low dose D-lysergic acid diethylamide (LSD) D-Tartrate (MM-120) as treatment for ADHD in adults: a multi-center, randomized, double- blind, placebo-controlled Phase 2a Proof of Concept Trial
Description Lysergic acid diethylamide (LSD) is synthetically derived from the fungus, Claviceps purpuria. Several isomers of this compound exist, although only the D-isomer is considered active. LSD was first synthesized by Albert Hofmann in 1938 in a search for an analeptic drug. After finding its psychogenic activity, it was marketed by Sandoz laboratories under the name Delysid?. It was also reportedly used by the Central Intelligence Agency as a tool for interrogation. Due to its potential for ‘bad trips,’ ‘flashbacks,’ and potential risk for brain injury, LSD was banned federally in 1966 and is currently only used illicitly. LSD is chemically similar to other naturally occurring lysergamides found in multiple species of morning glory.
Uses LSD is obtained by partial synthesis fromD-lysergic acid. It is also produced bymicrobial reaction of Claviceps paspali overthe hydroxylethylamide. It is a well-knownhallucinogen and a drug of abuse, listed asa controlled substance in the U.S. Code ofFederal Regulations (Title 21, Part 1308.11,1987). It is used as an antagonist to serotoninand in the study and treatment of mentaldisorders. Labelled Lysergide (L488010) Potent hallucinogen; non-selective serotonin receptor agonist. Has been used experimentally as adjunct in study and treatment of mental disorders. Controlled substance.

Technology Process of Lysergide

There total 10 articles about Lysergide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%