7-Iodopyrazolo[1,5-a]pyridine

Base Information

Chemical Name:7-Iodopyrazolo[1,5-a]pyridine
CAS No.:319432-22-9
Molecular Formula:C7H5IN2
Molecular Weight:244.035
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70460950
Nikkaji Number:J1.701.798E
Wikidata:Q82285145
Mol file:319432-22-9.mol

Synonyms:7-Iodopyrazolo[1,5-a]pyridine;319432-22-9;7-IODO-PYRAZOLO[1,5-A]PYRIDINE;7-iodoH-pyrazolo[1,5-a]pyridine;SCHEMBL3777508;DTXSID70460950;7-Iodo-pyrazolo[1,5-a] pyridine;AMY30455;MFCD08752620;AKOS016005810;AB48943;AS-40485;CS-0005377;FT-0767579;EN300-1165531

Suppliers and Price of 7-Iodopyrazolo[1,5-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
7-Iodo-pyrazolo[1,5-a]pyridine 96%
100mg
$ 137.00

Crysdot
7-Iodopyrazolo[1,5-a]pyridine 95+%
5g
$ 1369.00

Crysdot
7-Iodopyrazolo[1,5-a]pyridine 95+%
1g
$ 455.00

Chemenu
7-Iodo-pyrazolo[1,5-a]pyridine 95%
1g
$ 430.00

Chemenu
7-Iodo-pyrazolo[1,5-a]pyridine 95%
5g
$ 1290.00

American Custom Chemicals Corporation
PYRAZOLO[1,5-A]PYRIDINE, 7-IODO- 95.00%
1G
$ 1515.94

Alichem
7-Iodopyrazolo[1,5-a]pyridine
5g
$ 1366.20

Alichem
7-Iodopyrazolo[1,5-a]pyridine
1g
$ 478.40

Total 12 raw suppliers

Chemical Property of 7-Iodopyrazolo[1,5-a]pyridine

Chemical Property:

PKA:1.79±0.30(Predicted)
PSA：17.30000
Density:2.01g/cm³
LogP:1.93890
Storage Temp.:2-8°C(protect from light)
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:243.94975
Heavy Atom Count:10
Complexity:129

Purity/Quality:

97% ^*data from raw suppliers

7-Iodo-pyrazolo[1,5-a]pyridine 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=CC=NN2C(=C1)I

Technology Process of 7-Iodopyrazolo[1,5-a]pyridine

There total 3 articles about 7-Iodopyrazolo[1,5-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 274-56-6
3-azaindolizine

: 319432-22-9
7-Iodopyrazolo[1,5-a]pyridine

Guidance literature:: 3-azaindolizine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

With 1,2-Diiodoethane; In tetrahydrofuran; hexane; at -78 ℃; for 3h;
DOI:10.1055/s-2000-8215

Reference yield: 82.0%

: 7-(Tributylstannyl)pyrazolo[1,5-a]pyridine

: 319432-22-9
7-Iodopyrazolo[1,5-a]pyridine

Guidance literature:: With iodine; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1055/s-2000-8215

Reference yield:

: 16205-44-0
Pyrazolo<1,5-a>pyridin-3-carbonsaeureethylester

: 319432-22-9
7-Iodopyrazolo[1,5-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 2 h / 110 °C / Inert atmosphere

2.1: 2,2,6,6-tetramethylpiperidinyl magnesium chloride-lithium chloride / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

2.2: 1 h / -78 - 25 °C / Inert atmosphere

With sulfuric acid; 2,2,6,6-tetramethylpiperidinyl magnesium chloride-lithium chloride; In tetrahydrofuran;
DOI:10.1021/acs.orglett.8b01204