Phenazine-2,3-diamine

Base Information

• Chemical Name: Phenazine-2,3-diamine
• CAS No.: 655-86-7
• Molecular Formula: C12H10 N4
• Molecular Weight: 210.238
• Hs Code.: 2933990090
• European Community (EC) Number: 211-512-0
• UNII: 0B20H27U1Y
• DSSTox Substance ID: DTXSID40984097
• Nikkaji Number: J205.948G
• Wikidata: Q27236559
• ChEMBL ID: CHEMBL274921
• Mol file: 655-86-7.mol

Synonyms:2,3-diaminophenazine

Chemical Property of Phenazine-2,3-diamine

Chemical Property:

• Appearance/Colour: WHITE TO BROWN POWDER, CRYSTALS OR. CRYSTALLINE POWDER AND/OR CHUNKS
• Vapor Pressure: 4.78E-10mmHg at 25°C
• Melting Point: >300ºC
• Refractive Index: 1.5000 (estimate)
• Boiling Point: 491 °C at 760 mmHg
• PKA: 4.24±0.30(Predicted)
• Flash Point: 282.7 °C
• PSA: 77.82000
• Density: 1.414 g/cm³
• LogP: 3.10980
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 210.090546336
• Heavy Atom Count: 16
• Complexity: 231

Purity/Quality:

97% ^*data from raw suppliers

2,3-Phenazinediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): XiXn
• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N
• General Description: **2,3-Diaminophenazine (DAP)** is a Raman-active compound formed through the catalytic oxidation of *o*-phenylenediamine (OPD) in the presence of reactive oxygen species (ROS) or metal-based catalysts. It serves as a key product in colorimetric and surface-enhanced Raman scattering (SERS) assays for detecting analytes like H₂O₂, glucose, and mercury ions due to its strong SERS signal and distinct optical properties. DAP's formation is leveraged in sensor applications, where its generation correlates with catalytic activity, such as peroxidase-like behavior in metal-organic frameworks (MOFs) or nanoparticle systems. Its utility spans biosensing, environmental monitoring, and diagnostic platforms.

Technology Process of Phenazine-2,3-diamine

There total 50 articles about Phenazine-2,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,2-diamino-benzene (95-54-5) → 2,3-diaminephenazine (655-86-7)

Guidance literature:

With iron(III) chloride; In water; at 20 ℃; for 5h;

DOI:10.1139/v11-094

Reference yield: 78.0%

1,2-diamino-benzene (95-54-5) → 2,3-diaminephenazine (655-86-7) + 2-amino-3-hydroxy-phenazine (4569-77-1)

Guidance literature:

With hydrogenchloride; iron(III) chloride; at 20 ℃;

DOI:10.1080/10426500701415980

Reference yield: 64.3%

cyclohexa-1,4-diene (1165952-92-0) + 1,2-diamino-benzene (95-54-5) → 2,3-diaminephenazine (655-86-7)

Guidance literature:

With thorium(IV) nitrate; oxygen; In water; at 80 ℃;

DOI:10.1016/j.tetlet.2015.12.058

upstream raw materials:

benzofurazan oxide

acetic acid

1,2-diamino-benzene

o-phenylenediamine dihydrochloride

Downstream raw materials:

2,3-Bis-acetylamino-phenazin

2-(phenyl)-1H-imidazo[4,5-b]phenazine

2-(4-methoxyphenyl)-1H-imidazo[4,5-b]phenazine

5,12-dihydro-5,7,12,14-tetraazapentacene