2-(5-methoxy-1H-indol-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:2-(5-methoxy-1H-indol-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine
CAS No.:348640-18-6
Molecular Formula:C23H19N3O3S
Molecular Weight:417.488
Hs Code.:
Mol file:348640-18-6.mol

Synonyms:2-(5-methoxy-1H-indol-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine;Benzofuran,3-(2-iodoethyl)-5-methoxy;2-(5-methoxy-1-benzofuran-3-yl)ethyl iodide;

Suppliers and Price of 2-(5-methoxy-1H-indol-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-(5-methoxy-1H-indol-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:698.041°C at 760 mmHg
Flash Point:375.962°C
PSA：85.36000
Density:1.367g/cm³
LogP:5.81940

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(5-methoxy-1H-indol-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine

There total 6 articles about 2-(5-methoxy-1H-indol-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 348640-10-8
2-iodo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

: 348640-19-7
C₁₄H₁₈BNO₅

: 348640-18-6
2-(5-methoxy-1H-indol-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In DMF (N,N-dimethyl-formamide); water; at 20 ℃; for 4h; Heating / reflux;

Reference yield:

: 348640-02-8
1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine

: 348640-18-6
2-(5-methoxy-1H-indol-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: n-butyllithium; iodine / tetrahydrofuran

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; iodine; sodium hydrogencarbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1111/j.1747-0285.2010.00991.x

Reference yield:

: 271-63-6
7-Azaindole

: 348640-18-6
2-(5-methoxy-1H-indol-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / water; toluene

2: n-butyllithium; iodine / tetrahydrofuran

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; iodine; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; sodium hydroxide; In tetrahydrofuran; water; N,N-dimethyl-formamide; toluene;
DOI:10.1111/j.1747-0285.2010.00991.x