3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone

Base Information

Chemical Name:3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone
CAS No.:83344-22-3
Molecular Formula:C12H11BrO3
Molecular Weight:283.12
Hs Code.:2914700090
DSSTox Substance ID:DTXSID10573715
Mol file:83344-22-3.mol

Synonyms:83344-22-3;3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone;3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-naphthalen-1-one;3-Acetyl-5-bromo-8-hydroxy-3,4-dihydronaphthalen-1(2H)-one;3-acetyl-5-bromo-8-hydroxy-1,2,3,4-tetrahydronaphthalen-1-one;DTXSID10573715;1(2H)-Naphthalenone, 3-acetyl-5-bromo-3,4-dihydro-8-hydroxy-;MFCD11501103;AKOS028113928;AS-70398;CS-0060074

Suppliers and Price of 3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-ACETYL-5-BROMO-8-HYDROXY-3,4-DIHYDRO-2H-1-NAPHTHALENONE 95.00%
1G
$ 1085.42

Total 5 raw suppliers

Chemical Property of 3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone

Chemical Property:

Boiling Point:447.1±45.0 °C(Predicted)
PKA:7.59±0.40(Predicted)
PSA：54.37000
Density:1.585±0.06 g/cm3(Predicted)
LogP:2.48880
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:281.98916
Heavy Atom Count:16
Complexity:315

Purity/Quality:

97% ^*data from raw suppliers

3-ACETYL-5-BROMO-8-HYDROXY-3,4-DIHYDRO-2H-1-NAPHTHALENONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CC2=C(C=CC(=C2C(=O)C1)O)Br

Technology Process of 3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone

There total 1 articles about 3-Acetyl-5-bromo-8-hydroxy-3,4-dihydro-2H-1-naphthalenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 83344-21-2
3-Acetyl-4-(2-bromo-5-hydroxyphenyl)butyric acid

: 83344-22-3
2-Acetyl-8-bromo-5-hydroxy-1,2,3,4-tetrahydronaphthalene-4-one

Guidance literature:: With sulfuric acid; Ambient temperature;
DOI:10.1016/S0040-4039(00)87356-6

Reference yield:

: 83344-22-3
2-Acetyl-8-bromo-5-hydroxy-1,2,3,4-tetrahydronaphthalene-4-one

: 83344-25-6
2-Acetyl-5-(2-carbomethoxy-6-methoxybenzoyloxy)-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / H₂ / PtO₂ / ethanol / 6 h / 760 Torr

2: 90 percent / (CF₃CO)2O / CH₂Cl₂ / 4 h / Ambient temperature

With hydrogen; trifluoroacetic anhydride; platinum(IV) oxide; In ethanol; dichloromethane;

Reference yield:

: 83344-22-3
2-Acetyl-8-bromo-5-hydroxy-1,2,3,4-tetrahydronaphthalene-4-one

: 97006-24-1
2-Acetyl-5-hydroxy-6-(2-carbomethoxy-6-methoxybenzoyl)-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 3 steps

1: 45 percent / H₂ / PtO₂ / ethanol / 6 h / 760 Torr

2: 90 percent / (CF₃CO)2O / CH₂Cl₂ / 4 h / Ambient temperature

3: 60 percent / BF₃*Et₂O / 0.08 h / 130 °C

With boron trifluoride diethyl etherate; hydrogen; trifluoroacetic anhydride; platinum(IV) oxide; In ethanol; dichloromethane;