BENZYL 3-N,N-DIBENZYLAMINO-2-FLUOROPROPANOATE

Base Information

• Chemical Name: BENZYL 3-N,N-DIBENZYLAMINO-2-FLUOROPROPANOATE
• CAS No.: 887352-80-9
• Molecular Formula: C24H24FNO2
• Molecular Weight: 377.458
• Hs Code.: 2922499990
• Mol file: 887352-80-9.mol

Synonyms:3-Dibenzylamino-2-fluoropropionic acid, benzylester;

Chemical Property of BENZYL 3-N,N-DIBENZYLAMINO-2-FLUOROPROPANOATE

Chemical Property:

• Vapor Pressure: 1.1E-09mmHg at 25°C
• Boiling Point: 488.3°C at 760 mmHg
• Flash Point: 249.1°C
• PSA: 29.54000
• Density: 1.156g/cm³
• LogP: 4.77030
• Solubility.: Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol

Purity/Quality:

98%Min ^*data from raw suppliers

Benzyl 3-N,N-Dibenzylamino-2-fluoropropanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZYL 3-N,N-DIBENZYLAMINO-2-FLUOROPROPANOATE

There total 1 articles about BENZYL 3-N,N-DIBENZYLAMINO-2-FLUOROPROPANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(S)-benzyl 2-(dibenzylamino)-3-hydroxypropanoate (82770-40-9) → N,N-dibenzyl-α-fluoro-β-alanine benzyl ester (887352-80-9)

Guidance literature:

With diethylamino-sulfur trifluoride; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1021/ja00385a070

Reference yield:

N,N-dibenzyl-α-fluoro-β-alanine benzyl ester (887352-80-9) → (RS)-3-amino-2-fluoropropionic acid (3821-81-6)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1021/ja00385a070

upstream raw materials:

(S)-benzyl 2-(dibenzylamino)-3-hydroxypropanoate

Downstream raw materials:

(RS)-3-amino-2-fluoropropionic acid

Refernces