N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine

Base Information

• Chemical Name: N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine
• CAS No.: 252944-01-7
• Molecular Formula: C7H11N5O2
• Molecular Weight: 197.19
• Mol file: 252944-01-7.mol

Synonyms:2,6-Pyridinediamine, N6-(2-aminoethyl)-3-nitro-;

Chemical Property of N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine

Chemical Property:

• Boiling Point: 455.398 °C at 760 mmHg
• PKA: 8.98±0.10(Predicted)
• Flash Point: 229.217 °C
• PSA: 126.01000
• Density: 1.445 g/cm³
• LogP: 1.16920
• Solubility.: DMSO

Purity/Quality:

97% ^*data from raw suppliers

N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine

There total 3 articles about N6-(2-Aminoethyl)-3-nitro-2,6-pyridinediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-amino-6-chloro-3-nitropyridine (27048-04-0) → 2-(2-aminoethyl)amino-6-amino-5-nitropyridine (252944-01-7)

Guidance literature:

In methanol; ethyl acetate; ethylenediamine; acetonitrile;

Reference yield:

2-amino-6-chloro-3-nitropyridine (27048-04-0) + ethylenediamine (107-15-3,85404-18-8) → 2-(2-aminoethyl)amino-6-amino-5-nitropyridine (252944-01-7)

Guidance literature:

In acetonitrile; at 75 - 80 ℃; for 12h;

Reference yield:

2,6-dicholoro-3-nitropyridine (16013-85-7,136901-10-5) + 2-amino-6-chloro-3-nitropyridine (27048-04-0) → 2-(2-aminoethyl)amino-6-amino-5-nitropyridine (252944-01-7)

Guidance literature:

With ethylenediamine;

upstream raw materials:

2-amino-6-chloro-3-nitropyridine

ethylenediamine

2,6-dicholoro-3-nitropyridine

Downstream raw materials:

N₆-{2-[4-(2,4-dichlorophenyl)-5-morpholin-4-ylpyrimidin-2-ylamino]ethyl}-3-nitropyridine-2,6-diamine

N-[2-[2-(6-amino-5-nitropyridin-2-ylamino)ethylamino]-4-(2,4-dichlorophenyl)pyrimidin-5-yl]acetamide

N₂-[2-(6-amino-5-nitropyridin-2-ylamino)ethyl]-4-(2,4-dichlorophenyl)pyrimidine-2,5-diamine

N₂-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethyl)-5-nitropyridine-2,6-diamine

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