1-(5-Fluoropyridin-2-yl)ethanone

Base Information

• Chemical Name: 1-(5-Fluoropyridin-2-yl)ethanone
• CAS No.: 915720-54-6
• Molecular Formula: C7H6FNO
• Molecular Weight: 139.129
• Hs Code.: 2933399990
• Mol file: 915720-54-6.mol

Synonyms:1-(5-fluoro-pyridine-2-yl)-ethanone;QC-956;1-(5-fluoro-pyridin-2-yl)-ethanone;1-(5-fluoropyridin-2-yl)ethan-1-one;2-ACETYL-5-FLUOROPYRIDINE;

Chemical Property of 1-(5-Fluoropyridin-2-yl)ethanone

Chemical Property:

• Boiling Point: 193 oC
• PKA: 0.58±0.10(Predicted)
• Flash Point: 71 oC
• PSA: 29.96000
• Density: 1.175
• LogP: 1.42330
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

1-(5-Fluoropyridin-2-yl)ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(5-Fluoropyridin-2-yl)ethanone

There total 5 articles about 1-(5-Fluoropyridin-2-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-fluoropicolinonitrile (327056-62-2) + methylmagnesium bromide (75-16-1) → 1-(5-fluoropyridin-2-yl)ethan-1-one (915720-54-6)

Guidance literature:

In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 7.25h; Inert atmosphere;

Reference yield: 85.0%

2-bromo-5-fluoropyridine (41404-58-4) + N,N-dimethyl acetamide (127-19-5,116057-81-9) → 1-(5-fluoropyridin-2-yl)ethan-1-one (915720-54-6)

Guidance literature:

With n-butyllithium; In hexane; toluene; at -70 - -50 ℃; for 1h;

Reference yield: 82.0%

2-bromo-5-fluoropyridine (41404-58-4) + tributyl(1-ethoxyvinyl)stannane (97674-02-7) → 1-(5-fluoropyridin-2-yl)ethan-1-one (915720-54-6)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In acetonitrile; for 70h; Heating / reflux;

upstream raw materials:

5-fluoropicolinonitrile

methylmagnesium bromide

2-bromo-5-fluoropyridine

tributyl(1-ethoxyvinyl)stannane

Downstream raw materials:

1-(5-fluoropyridin-2-yl)ethanol

[(1E)-1-(5-fluoropyridin-2-yl)ethylidene][(1S)-1-phenylethyl]amine

C₁₈H₁₉FN₂O₃S

2-(5-fluoropyridin-2-yl)-2-oxoethyl 2,4-dinitrobenzenesulfonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 915720-54-6 1-(5-Fluoropyridin-2-yl)ethanone

Send

Send

Metric Ton KG G Pound L ML

Send

Send