IsopyrazaM

Base Information

• Chemical Name: IsopyrazaM
• CAS No.: 881685-58-1
• Molecular Formula: C20H23F2N3O
• Molecular Weight: 359.419
• Mol file: 881685-58-1.mol

Synonyms:3-(difluoromethyl)-1-methyl-N-((1rs,4sr,9sr)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide

Chemical Property of IsopyrazaM

Chemical Property:

• Vapor Pressure: 0-0Pa at 20-25℃
• Boiling Point: 407.0±45.0 °C(Predicted)
• PKA: 12.27±0.40(Predicted)
• PSA: 46.92000
• Density: 1.37±0.1 g/cm3(Predicted)
• LogP: 4.92980

Purity/Quality:

Isopyrazam PESTANAL ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 63-40-43-50/53
• Safety Statements: 36/37-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Isopyrazam is a pesticide which acts as a succinate dehydrogenase inhibiting fungicide used in mold control.

Technology Process of IsopyrazaM

There total 9 articles about IsopyrazaM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-methyl-3-(difluoromethyl)-1H-pyrazole-4-amide (925689-10-7) + 5-chloro-9-isopropyl-1,2,3,4-tetrahydro-1,4-methano-naphthalene (1233219-30-1) → isopyrazam (881685-58-1)

Guidance literature:

With potassium carbonate; trans-N,N'-dimethyl-1,2-cyclohexyldiamine; copper(I) bromide; In N,N-dimethyl-formamide; at 150 ℃; Product distribution / selectivity; Inert atmosphere;

Reference yield: 82.0%

N-[1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]amine (1196531-06-2) + 3‐difluoromethyl‐1‐methylpyrazole-4-carbonyl chloride (141573-96-8) → isopyrazam (881685-58-1)

Guidance literature:

In toluene; at 25 - 85 ℃; under 262.526 Torr;

Reference yield: 76.0%

3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid (176969-34-9) + N-[1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]amine (1196531-06-2) → isopyrazam (881685-58-1)

Guidance literature:

3,5-bis-trifluromethylphenylboronic acid; In toluene; Product distribution / selectivity; Inert atmosphere; Reflux; Molecular sieves;

upstream raw materials:

1-methyl-3-(difluoromethyl)-1H-pyrazole-4-amide

5-chloro-9-isopropyl-1,2,3,4-tetrahydro-1,4-methano-naphthalene

N-[1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]amine

4-bromo-3-(difluoromethyl)-1-methyl-1H-pyrazole