3-（hydroxymethyl）-3-nitro-1-(4-octylphenyl)-Ben

Base Information

Chemical Name:3-（hydroxymethyl）-3-nitro-1-(4-octylphenyl)-Ben
CAS No.:899822-99-2
Molecular Formula:C19H31NO5
Molecular Weight:353.459
Hs Code.:
Mol file:899822-99-2.mol

Synonyms:1-Hydroxy-3-nitrodeamino Fingolimod;3-(Hydroxymethyl)-3-nitro-1-(4-octylphenyl)-1,4-butanediol;

Suppliers and Price of 3-（hydroxymethyl）-3-nitro-1-(4-octylphenyl)-Ben

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
1-Hydroxy-3-nitrodeamino Fingolimod
25mg
$ 460.00

TRC
1-Hydroxy-3-nitrodeaminoFingolimod
250mg
$ 1190.00

Medical Isotopes, Inc.
1-Hydroxy-3-nitrodeaminoFingolimod
25 mg
$ 650.00

Total 20 raw suppliers

Chemical Property of 3-（hydroxymethyl）-3-nitro-1-(4-octylphenyl)-Ben

Chemical Property:

Boiling Point:556.1±50.0 °C(Predicted)
PKA:12.72±0.10(Predicted)
PSA：106.51000
Density:1.141
LogP:3.53640

Purity/Quality:

99%, ^*data from raw suppliers

1-Hydroxy-3-nitrodeamino Fingolimod ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-（hydroxymethyl）-3-nitro-1-(4-octylphenyl)-Ben

There total 8 articles about 3-（hydroxymethyl）-3-nitro-1-(4-octylphenyl)-Ben which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 899822-98-1
3-nitro-1-(4-octylphenyl)propan-1-ol

: 899822-99-2
3-(hydroxymethyl)-3-nitro-1-(4-octylphenyl)butane-1,4-diol

Guidance literature:: With triethylamine;
DOI:10.1080/00397911.2018.1536788

Reference yield:

: 928165-59-7
3-chloro-1-(4-octylphenyl)propan-1-one

: 899822-99-2
3-(hydroxymethyl)-3-nitro-1-(4-octylphenyl)butane-1,4-diol

Guidance literature:: Multi-step reaction with 3 steps

1: sodium nitrite / N,N-dimethyl-formamide / 4 - 6 h / 25 - 35 °C / Large scale

2: sodium tetrahydroborate / methanol

3: triethylamine

With sodium tetrahydroborate; triethylamine; sodium nitrite; In methanol; N,N-dimethyl-formamide;
DOI:10.1080/00397911.2018.1536788