5,8-Dioxa-10-azadispiro[2.0.4.3]undecane

Base Information

• Chemical Name: 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane
• CAS No.: 129321-60-4
• Molecular Formula: C8H13NO2
• Molecular Weight: 155.19
• Hs Code.: 2934999090
• Mol file: 129321-60-4.mol

Synonyms:5,8-Dioxa-10-azadispiro[2.0.4.3]undecane;{[2-(cyclopropylMethoxy)ethoxy]Methyl}(propyl)aMine

Chemical Property of 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane

Chemical Property:

• Boiling Point: 258.6±25.0 °C(Predicted)
• PKA: 9.10±0.20(Predicted)
• PSA: 30.49000
• Density: 1.23±0.1 g/cm3(Predicted)
• LogP: 0.44170
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

5,8-Dioxa-10-azadispiro[2.0.4.3]undecane 95-98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane

There total 2 articles about 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-benzyl-7,7-ethylenedioxy-5-azaspiro[2.4]heptane (147011-43-6) → 5,8-dioxa-10-azadispiro[2.0.44.33]undecane (129321-60-4)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol;

DOI:10.1016/j.bmcl.2009.03.025

Reference yield:

7,7-Ethylenedioxy-5-[1-(R)-phenylethyl]-5-azaspiro[2.4]heptane → 5,8-dioxa-10-azadispiro[2.0.44.33]undecane (129321-60-4)

Guidance literature:

palladium; In ethanol;

Reference yield: 80.0%

3-(pyrimidin-5-yl)-benzaldehyde (640769-70-6) + 5,8-dioxa-10-azadispiro[2.0.44.33]undecane (129321-60-4) + phosphonic acid diethyl ester (762-04-9) → diethyl [5,8-dioxa-10-azadispiro[2.0.4.3]undec-10-yl[3-(5-pyrimidinyl)phenyl]methyl]phosphonate

Guidance literature:

With hydrogen trititanate; In neat (no solvent); at 20 ℃; for 0.25h; Green chemistry;

DOI:10.1039/c5nj01914a

upstream raw materials:

5-benzyl-7,7-ethylenedioxy-5-azaspiro[2.4]heptane

Downstream raw materials:

C₁₄H₁₅FN₂O₄

3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)-nitrobenzene

C₁₄H₁₆F₂N₂O₂

(S)-N-{{3-[3,5-difluoro-4-(7-fluoro-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl}acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 129321-60-4 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane

Send

Send

Metric Ton KG G Pound L ML

Send

Send