Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside

Base Information

Chemical Name:Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside
CAS No.:206186-94-9
Molecular Formula:C34H46O6Si
Molecular Weight:578.821
Hs Code.:
Mol file:206186-94-9.mol

Synonyms:Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside;Methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldimethylsilyl-a-D-mannopyranoside

Suppliers and Price of Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL-2,3,4-TRI-O-BENZYL-6-O-TERT-BUTYLDIMETHYLSILYL-ALPHA-D-MANNOPYRANOSIDE 95.00%
5MG
$ 498.52

Total 6 raw suppliers

Chemical Property of Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside

Chemical Property:

PSA：55.38000
LogP:7.13570

Purity/Quality:

97% ^*data from raw suppliers

METHYL-2,3,4-TRI-O-BENZYL-6-O-TERT-BUTYLDIMETHYLSILYL-ALPHA-D-MANNOPYRANOSIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside

There total 5 articles about Methyl-6-O-(tert.-butyldimethylsilyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 100-39-0
benzyl bromide

: 74247-81-7
6-O-tert-butyldimethylsilanyl-1-O-methyl-α-D-mannopyranoside

: 206186-94-9,166592-73-0
methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/j.carres.2003.10.007

Reference yield:

: 617-04-9
(2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol

: 206186-94-9,166592-73-0
methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / triethylamine; 4-(dimethylamino)pyridine / dimethylformamide / 12 h / 20 °C

2: tetrabutylammonium iodide; NaH / dimethylformamide / 24 h / 20 °C

With dmap; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1021/jo070229y

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 206186-94-9,166592-73-0
methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / triethylamine; 4-(dimethylamino)pyridine / dimethylformamide / 12 h / 20 °C

2: tetrabutylammonium iodide; NaH / dimethylformamide / 24 h / 20 °C

With dmap; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1021/jo070229y