N-Methyl-N-phenylpropenamide

Base Information

• Chemical Name: N-Methyl-N-phenylpropenamide
• CAS No.: 6273-94-5
• Molecular Formula: C21H18N2O4S
• Molecular Weight: 161.203
• Mol file: 6273-94-5.mol

Synonyms:Acrylsaeure-methylanilid;N-Methyl-acrylanilid;N-Methyl-N-phenylpropenamide;N-methyl-acrylanilide;

Chemical Property of N-Methyl-N-phenylpropenamide

Chemical Property:

• Vapor Pressure: 7.99E-14mmHg at 25°C
• Boiling Point: 224.7°Cat760mmHg
• Flash Point: 89.3°C
• PSA: 20.31000
• Density: 1.056g/cm³
• LogP: 1.83540

Purity/Quality:

99% ^*data from raw suppliers

n-Methyl-n-phenylprop-2-enamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Methyl-N-phenylpropenamide

There total 10 articles about N-Methyl-N-phenylpropenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-acryloylaniline (2210-24-4) + methyl iodide (74-88-4) → N-methyl-N-phenylacrylamide (6273-94-5)

Guidance literature:

N-acryloylaniline; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1039/d0ob01104e

Reference yield: 72.0%

acryloyl chloride (814-68-6,25189-84-8) + N-methylaniline (100-61-8) → N-methyl-N-phenylacrylamide (6273-94-5)

Guidance literature:

acryloyl chloride; N-methylaniline; In dichloromethane; chloroform; for 0.0833333h;

With Amberlyst A₂₆ (OH-form); In dichloromethane; chloroform; for 0.0833333h;

DOI:10.1021/ol503486t

Reference yield: 19.0%

2-bromo-N-methyl-N-phenylacrylamide (90844-75-0) → N-methyl-N-phenylacrylamide (6273-94-5) + 2-bromo-4-methylene-pentanedioic acid bis-(methyl-phenyl-amide)

Guidance literature:

With samarium diiodide; In tetrahydrofuran-d8; at -78 ℃; for 0.0833333h;

DOI:10.1039/b006495p

upstream raw materials:

3-chloro-N-methyl-N-phenylpropanamide

acryloyl chloride

N-methylaniline

acetylene

Downstream raw materials:

5-(diisopropylcarbamoyl)-N-methyl-N-phenyl-5-heptenamide

N,N-diisopropyl-N',2-dimethyl-N'-phenyl-1,4-cyclopentanedicarboxamide

(E)-4-(phenylthio)-5-(N,N-diisopropylcarbamoyl)-N-methyl-N-phenyl-4-hexenamide

(E)-6-(phenylthio)-5-(N,N-diisopropylcarbamoyl)-N-methyl-N-phenyl-5-hexenamide