1-Cbz-3-aminopyrrolidine hydrochloride

Base Information

• Chemical Name: 1-Cbz-3-aminopyrrolidine hydrochloride
• CAS No.: 1159822-27-1
• Molecular Formula: C12H16N2O2.ClH
• Molecular Weight: 256.72858
• Hs Code.: 2933990090
• Mol file: 1159822-27-1.mol

Synonyms:Benzyl 3-aminopyrrolidine-1-carboxylate hydrochloride;Benzyl 3-amino-1-pyrrolidinecarboxylate hydrochloride (1:1);

Chemical Property of 1-Cbz-3-aminopyrrolidine hydrochloride

Chemical Property:

• PSA: 55.56000
• LogP: 2.79640
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-Cbz-3-aminopyrrolidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Cbz-3-aminopyrrolidine hydrochloride

There total 1 articles about 1-Cbz-3-aminopyrrolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-pyrrolidinecarboxylic acid,phenylmethyl ester (185057-49-2) → 1-Cbz-3-aminopyrrolidine hydrochloride (1159822-27-1)

Guidance literature:

With hydrogenchloride; acetic acid; In methoxybenzene; for 0.333333h;

Reference yield:

1-Cbz-3-aminopyrrolidine hydrochloride (1159822-27-1) + N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → 1-Cbz-3-[(9-fluorenyl)methoxycarbonyl]aminopyrrolidine (400653-41-0)

Guidance literature:

With sodium carbonate; In 1,4-dioxane; water; at 20 ℃; for 24h;

Reference yield:

1-Cbz-3-aminopyrrolidine hydrochloride (1159822-27-1) + 1-{[(1,1-dimethylethyl)oxy]carbonyl}-1H-benzimidazole-5-carboxylic acid (400653-36-3) → 1-Cbz-3-[[1-(t-butyloxycarbonyl)benzimidazol-5-yl]-carbonyl]aminopyrrolidine (400653-37-4)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 24h;

upstream raw materials:

(S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-pyrrolidinecarboxylic acid,phenylmethyl ester

Downstream raw materials:

1-Cbz-3-[(9-fluorenyl)methoxycarbonyl]aminopyrrolidine

1-Cbz-3-[[1-(t-butyloxycarbonyl)benzimidazol-5-yl]-carbonyl]aminopyrrolidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1159822-27-1 1-Cbz-3-aminopyrrolidine hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send