Ethyl 2-formyloxazole-4-carboxylate

Base Information

Chemical Name:Ethyl 2-formyloxazole-4-carboxylate
CAS No.:181633-60-3
Molecular Formula:C7H7NO4
Molecular Weight:169.137
Hs Code.:2934999090
European Community (EC) Number:877-538-5
DSSTox Substance ID:DTXSID10442013
Nikkaji Number:J1.936.050D
Wikidata:Q82259060
Mol file:181633-60-3.mol

Synonyms:Ethyl 2-formyloxazole-4-carboxylate;181633-60-3;Ethyl 2-formyl-1,3-oxazole-4-carboxylate;Ethyl2-formyloxazole-4-carboxylate;4-Oxazolecarboxylic acid, 2-formyl-, ethyl ester;SCHEMBL856356;DTXSID10442013;GCCVOQPMHVWBLV-UHFFFAOYSA-N;AB76348;AT18587;CS-0217231;2-Formyloxazole-4-carboxylic acid ethyl ester;EN300-716161;2-FORMYL-OXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;Z1263714842

Suppliers and Price of Ethyl 2-formyloxazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-formyloxazole-4-carboxylate 95+%
1g
$ 772.00

Chemenu
ethyl2-formyloxazole-4-carboxylate 95%
1g
$ 729.00

American Custom Chemicals Corporation
ETHYL-2-FORMYLOXAZOLE-4-CARBOXYLATE 95.00%
5MG
$ 499.13

Total 8 raw suppliers

Chemical Property of Ethyl 2-formyloxazole-4-carboxylate

Chemical Property:

Boiling Point:282.9±32.0 °C(Predicted)
PKA:-4.49±0.10(Predicted)
PSA：69.40000
Density:1.285±0.06 g/cm3(Predicted)
LogP:0.66380
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:169.03750770
Heavy Atom Count:12
Complexity:182

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-formyloxazole-4-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=COC(=N1)C=O

Technology Process of Ethyl 2-formyloxazole-4-carboxylate

There total 5 articles about Ethyl 2-formyloxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 181633-66-9
2-(1,2-Dihydroxy-2-phenyl-ethyl)-oxazole-4-carboxylic acid ethyl ester

: 181633-60-3
ethyl 2-formyl-1, 3-oxazole-4-carboxylate

Guidance literature:: With lead(IV) acetate; potassium carbonate; In methanol; at 0 ℃;
DOI:10.1021/jo960532r

Reference yield: 68.0%

: 132629-37-9
ethyl 2-[(E)-2-phenylethenyl]oxazole-4-carboxylate

: 181633-60-3
ethyl 2-formyl-1, 3-oxazole-4-carboxylate

Guidance literature:: With ruthenium trichloride; sodium periodate; silica gel; In dichloromethane; at 20 ℃;
DOI:10.1055/s-2003-41033

Reference yield:

: 70-23-5
ethyl Bromopyruvate

: 181633-60-3
ethyl 2-formyl-1, 3-oxazole-4-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 1) NaHCO₃, 2) TFAA / 1) THF, reflux, 23 h, 2) THF, 0 deg C

2: 85 percent / OsO₄, Me₃NO, H₂O / acetone

3: 84 percent / Pb(OAc)4, K₂CO₃ / methanol / 0 °C

With lead(IV) acetate; osmium(VIII) oxide; trimethylamine-N-oxide; water; sodium hydrogencarbonate; potassium carbonate; trifluoroacetic anhydride; In methanol; acetone;
DOI:10.1021/jo960532r