2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)-

Base Information

Chemical Name:2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)-
CAS No.:441741-65-7
Molecular Formula:C22H24N2O2
Molecular Weight:348.445
Hs Code.:2933990090
Mol file:441741-65-7.mol

Synonyms:methyl (E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate;(2E)-3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenoic acid methyl ester;2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)-

Suppliers and Price of 2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
methyl(E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate 95%
1g
$ 632.00

American Custom Chemicals Corporation
(E)-METHYL 3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)ACRYLATE 95.00%
5MG
$ 505.10

Alichem
(E)-Methyl3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate
1g
$ 598.40

Total 17 raw suppliers

Chemical Property of 2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)-

Chemical Property:

PSA：54.12000
LogP:4.38570
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

methyl(E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)-

There total 10 articles about 2-Propenoic acid, 3-[4-[[[2-(2-Methyl-1H-indol-3-yl)ethyl]aMino]Methyl]phenyl]-, Methyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 2731-06-8
2-methyltryptamine

: 7560-50-1,71093-79-3,58045-41-3
methyl (2E)-3-(4-formylphenyl)acrylate

: 441741-65-7
(E)-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]acrylic acid methyl ester

Guidance literature:: 2-methyltryptamine; methyl (2E)-3-(4-formylphenyl)acrylate; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 1h; Molecular sieve;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; for 18h;
DOI:10.1016/j.chembiol.2021.04.004

Reference yield: 57.2%

: 1067-74-9
Methyl diethylphosphonoacetate

: 4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]benzaldehyde

: 441741-65-7
(E)-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]acrylic acid methyl ester

Guidance literature:: Methyl diethylphosphonoacetate; With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; In acetonitrile; at 20 ℃; for 0.25h; Inert atmosphere;

4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]benzaldehyde; In acetonitrile; for 2h; Inert atmosphere;

Reference yield: 55.0%

: 2731-06-8
2-methyltryptamine

: 1067-74-9
Methyl diethylphosphonoacetate

: 73291-09-5
4-chloromethylbenzaldehyde

: 441741-65-7
(E)-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]acrylic acid methyl ester

Guidance literature:: 2-methyltryptamine; Methyl diethylphosphonoacetate; With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

4-chloromethylbenzaldehyde; In N,N-dimethyl-formamide; at 0 ℃; for 6h; Inert atmosphere;