4-CHLOROMETHYLBENZALDEHYDE; >95%DISCONTINUED 10/25/01

Base Information

• Chemical Name: 4-CHLOROMETHYLBENZALDEHYDE; >95%DISCONTINUED 10/25/01
• CAS No.: 73291-09-5
• Molecular Formula: C8H7ClO
• Molecular Weight: 154.596
• Hs Code.: 2913000090
• Mol file: 73291-09-5.mol

Synonyms:p-Tolualdehyde,a-chloro- (6CI,7CI);4-Formylbenzyl chloride;NSC 617411;p-(Chloromethyl)benzaldehyde;

Chemical Property of 4-CHLOROMETHYLBENZALDEHYDE; >95%DISCONTINUED 10/25/01

Chemical Property:

• Melting Point: 73 °C
• Boiling Point: 265.6±15.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.200±0.06 g/cm3(Predicted)
• LogP: 2.23790
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-(chloromethyl)benzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 4-CHLOROMETHYLBENZALDEHYDE is a chemical compound that was discontinued after October 25, 2001. Prior to its discontinuation, it had applications in various fields. In the field of organic chemistry, it could have been used as a reagent or intermediate in the synthesis of complex organic molecules, contributing to the production of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its unique chemical structure would have allowed chemists to introduce specific functional groups and structural motifs into target molecules. In the pharmaceutical industry, this compound might have played a role as an intermediate in the synthesis of drug candidates or as an ingredient in pharmaceutical formulations. Its precise role and significance would have varied depending on specific research or industrial requirements within each field, but it would have consistently played a pivotal role in advancing chemical synthesis, drug development, and materials innovation across diverse scientific and industrial applications prior to its discontinuation.

Technology Process of 4-CHLOROMETHYLBENZALDEHYDE; >95%DISCONTINUED 10/25/01

There total 30 articles about 4-CHLOROMETHYLBENZALDEHYDE; >95%DISCONTINUED 10/25/01 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-cyanobenzyl chloride (874-86-2) → 4-chloromethylbenzaldehyde (73291-09-5)

Guidance literature:

With diisobutylaluminium hydride; In chlorobenzene;

DOI:10.1007/s00726-010-0594-3

Reference yield: 94.0%

4-(hydroxymethyl)benzyl chloride (16473-35-1) → 4-chloromethylbenzaldehyde (73291-09-5)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/ja051179m

Reference yield: 92.0%

4-Vinylbenzyl chloride (1592-20-7,29296-32-0) → 4-chloromethylbenzaldehyde (73291-09-5)

Guidance literature:

With dihydrogen peroxide; In water; at 100 ℃; for 4h;

DOI:10.1002/adsc.201100630

upstream raw materials:

4-cyanobenzyl chloride

1-bromomethyl-4-chloromethylbenzene

4-(hydroxymethyl)benzaldehyde dimethyl acetal

4-<(triphenylmethoxy)methyl>benzyl chloride

Downstream raw materials:

5,10,15,20-tetrakis(p-chloromethylphenyl)porphyrin

4-(bromomethyl)benzaldehyde

(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]acrylic acid methyl ester hydrochloride

methyl (E)-3-(4-(chloromethyl)phenyl)acrylate

Refernces

• 1、 Eswaran, Sumesh,Shruthi, T. G.,Subramanian, Sangeetha. "Design, synthesis and study of antibacterial and antitubercular activity of quinoline hydrazone hybrids". . p. 137 - 147. Retrieved 2020/11/12.
• 2、 Emayavaramban,Ganesh Babu,Karvembu,Kadirvelu,Dharmaraj. "Gold nanoparticles supported on magnesium oxide nanorods for oxidation of alcohols". . p. 2517 - 2526. Retrieved 2016/03/19.