4-diphenyl-1-naphthalene boronic acid

Base Information

• Chemical Name: 4-diphenyl-1-naphthalene boronic acid
• CAS No.: 881811-83-2
• Molecular Formula: C22H17BO2
• Molecular Weight: 324.18000
• Hs Code.: 2931900090
• Mol file: 881811-83-2.mol

Synonyms:4-diphenyl-1-naphthalene boronic acid;

Chemical Property of 4-diphenyl-1-naphthalene boronic acid

Chemical Property:

• Boiling Point: 528.1±60.0 °C(Predicted)
• PKA: 8.56±0.30(Predicted)
• PSA: 40.46000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 3.85360

Purity/Quality:

98% ^*data from raw suppliers

4-Diphenyl-1-naphthaleneboronicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-diphenyl-1-naphthalene boronic acid

There total 5 articles about 4-diphenyl-1-naphthalene boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H21BO2 → 2,4-diphenyl-1-naphthylboronic acid (881811-83-2)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; hexane;

DOI:10.1021/ja058066n

Reference yield:

2,4-diphenyl-1-naphthylamine (881811-70-7) → 2,4-diphenyl-1-naphthylboronic acid (881811-83-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: aq. H₂SO₄ / 8 h / 50 °C

1.2: aq. NaNO₂ / 0.5 h / 0 °C

1.3: 79 percent / aq. KI / 4 h / Heating

2.1: n-BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C

2.2: hexane; tetrahydrofuran / 20 °C

3.1: 147 mg / aq. HCl / hexane; tetrahydrofuran

With hydrogenchloride; n-butyllithium; sulfuric acid; In tetrahydrofuran; hexane;

DOI:10.1021/ja058066n

Reference yield:

2,4-dibromo-1-naphthylamine (20191-76-8) → 2,4-diphenyl-1-naphthylboronic acid (881811-83-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 68 percent / Pd(OAc)2; PPh₃; Cs₂CO₃ / dimethylformamide / 12 h / 90 °C

2.1: aq. H₂SO₄ / 8 h / 50 °C

2.2: aq. NaNO₂ / 0.5 h / 0 °C

2.3: 79 percent / aq. KI / 4 h / Heating

3.1: n-BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C

3.2: hexane; tetrahydrofuran / 20 °C

4.1: 147 mg / aq. HCl / hexane; tetrahydrofuran

With hydrogenchloride; palladium diacetate; n-butyllithium; sulfuric acid; caesium carbonate; triphenylphosphine; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; 1.1: Suzuki-Miyaura coupling;

DOI:10.1021/ja058066n

upstream raw materials:

2,4-diphenyl-1-naphthylamine

2,4-dibromo-1-naphthylamine

1-amino-naphthalene

1-iodo-2,4-diphenylnaphthalene

Refernces