1-iodo-2,4-diphenylnaphthalene

Base Information

• Chemical Name: 1-iodo-2,4-diphenylnaphthalene
• CAS No.: 809274-71-3
• Molecular Formula: C₂₂H₁₅I
• Molecular Weight: 406.266
• Mol file: 809274-71-3.mol

Synonyms:1-iodo-2,4-diphenylnaphthalene

Chemical Property of 1-iodo-2,4-diphenylnaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-iodo-2,4-diphenylnaphthalene

There total 5 articles about 1-iodo-2,4-diphenylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2,4-diphenyl-1-naphthylamine (881811-70-7) → 1-iodo-2,4-diphenylnaphthalene (809274-71-3)

Guidance literature:

2,4-diphenyl-1-naphthylamine; With sulfuric acid; at 50 ℃; for 8h;

With sodium nitrite; at 0 ℃; for 0.5h;

With potassium iodide; for 4h; Heating;

DOI:10.1021/ja058066n

Reference yield:

2,4-dibromo-1-naphthylamine (20191-76-8) → 1-iodo-2,4-diphenylnaphthalene (809274-71-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 68 percent / Pd(OAc)2; PPh₃; Cs₂CO₃ / dimethylformamide / 12 h / 90 °C

2.1: aq. H₂SO₄ / 8 h / 50 °C

2.2: aq. NaNO₂ / 0.5 h / 0 °C

2.3: 79 percent / aq. KI / 4 h / Heating

With palladium diacetate; sulfuric acid; caesium carbonate; triphenylphosphine; In N,N-dimethyl-formamide; 1.1: Suzuki-Miyaura coupling;

DOI:10.1021/ja058066n

Reference yield:

1-amino-naphthalene (134-32-7) → 1-iodo-2,4-diphenylnaphthalene (809274-71-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 71 percent / NBS / CH₂Cl₂ / 0.5 h / 0 °C

2.1: 68 percent / Pd(OAc)2; PPh₃; Cs₂CO₃ / dimethylformamide / 12 h / 90 °C

3.1: aq. H₂SO₄ / 8 h / 50 °C

3.2: aq. NaNO₂ / 0.5 h / 0 °C

3.3: 79 percent / aq. KI / 4 h / Heating

With palladium diacetate; N-Bromosuccinimide; sulfuric acid; caesium carbonate; triphenylphosphine; In dichloromethane; N,N-dimethyl-formamide; 2.1: Suzuki-Miyaura coupling;

DOI:10.1021/ja058066n

upstream raw materials:

1,3-diphenylnaphthalene

2,4-diphenyl-1-naphthylamine

2,4-dibromo-1-naphthylamine

1-amino-naphthalene

Downstream raw materials:

2,4-diphenyl-1-naphthylboronic acid

1,3-diphenylnaphthalene

Refernces

• 1、 Ooi, Takashi,Uematsu, Yukitaka,Maruoka, Keiji. "Asymmetric Strecker reaction of aldimines using aqueous potassium cyanide by phase-transfer catalysis of chiral quaternary ammonium salts with a tetranaphthyl backbone". . p. 2548 - 2549. Retrieved 2007/10/03.