(S)-2,6-DIAMINO-HEXANOIC ACID BENZYL ESTER DIHYDROCHLORIDE

Base Information

• Chemical Name: (S)-2,6-DIAMINO-HEXANOIC ACID BENZYL ESTER DIHYDROCHLORIDE
• CAS No.: 16142-09-9
• Molecular Formula: C13H22Cl2N2O2
• Molecular Weight: 0
• Hs Code.: 2922499990
• Mol file: 16142-09-9.mol

Synonyms:(S)-Benzyl 2,6-diamino-hexanoate dihydrochloride;

Chemical Property of (S)-2,6-DIAMINO-HEXANOIC ACID BENZYL ESTER DIHYDROCHLORIDE

Chemical Property:

• PSA: 78.34000
• LogP: 4.19070
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(S)-Benzyl2,6-DiaminohexanoateDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2,6-DIAMINO-HEXANOIC ACID BENZYL ESTER DIHYDROCHLORIDE

There total 2 articles about (S)-2,6-DIAMINO-HEXANOIC ACID BENZYL ESTER DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-Lys(Boc)-OH (2483-46-7) → lysine benzyl ester hydrochloride (134143-21-8,16142-09-9)

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: hydrogenchloride / 1,4-dioxane / 16 h / 20 °C

With hydrogenchloride; caesium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;

Reference yield:

Boc-Lys-OH (13734-28-6) → lysine benzyl ester hydrochloride (134143-21-8,16142-09-9)

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: hydrogenchloride / 1,4-dioxane / 16 h / 20 °C

With hydrogenchloride; caesium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;

Reference yield: 71.0%

lysine benzyl ester hydrochloride (134143-21-8,16142-09-9) + 5-fluorouracil-1-acetic acid (56059-30-4) → C25H26F2N6O8 (1467575-47-8)

Guidance literature:

5-fluorouracil-1-acetic acid; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 ℃; for 0.416667h; Inert atmosphere;

lysine benzyl ester hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.2174/15701786113109990024

upstream raw materials:

Boc-Lys(Boc)-OH

Boc-Lys-OH

Downstream raw materials:

C₂₅H₂₆F₂N₆O₈