Welcome to LookChem.com Sign In|Join Free
  • or

2483-46-7

Post Buying Request

2483-46-7 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
(S)-2,6-Bis-tert-butoxycarbonylaminohexanoic acid Manufacturer/High quality/Best price/In stock
Cas No: 2483-46-7
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
2-amino-7-[(2-methylpropan-2-yl)oxy]-2-[(2-methylpropan-2-yl)oxy-oxomethyl]-7-oxoheptanoic acid
Cas No: 2483-46-7
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Pharmaceutical Grade CAS 2483-46-7 with competitive price
Cas No: 2483-46-7
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier
BLOOM TECH Advanced API/Technology support (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid CAS 2483-46-7
Cas No: 2483-46-7
No Data 1 Gram 3 Metric Ton/Month Shaanxi BLOOM TECH Co.,Ltd Contact Supplier
(S)-2,6-Bis-tert-butoxycarbonylaminohexanoic acid
Cas No: 2483-46-7
No Data 1 Gram 100 Metric Ton/Month CHANGCHUN WEIERSI IMPORT AND EXPORT TRADE CO.,LTD Contact Supplier
CAS NO.:2483-46-7
Cas No: 2483-46-7
No Data No Data 10000 Metric Ton/Month Henan Wentao Chemical Product Co., Ltd. Contact Supplier
N2,N6-Bis-(tert-butoxycarbonyl)-L-lysine
Cas No: 2483-46-7
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
L-Lysine,N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-
Cas No: 2483-46-7
No Data 1 Gram 10000 Metric Ton/Month Shanghai Upbio Tech Co.,Ltd Contact Supplier
(S)-2,6-Bis-tert-butoxycarbonylaminohexanoic acid CAS NO.2483-46-7CAS NO.: 2483-46-7
Cas No: 2483-46-7
No Data 1 Gram 10 Metric Ton/Month Hebei Guanlang Biotechnology Co., Ltd. Contact Supplier
(S)-2,6-Bis-tert-butoxycarbonylaminohexanoic acid CAS NO.2483-46-7 CAS NO.2483-46-7 JSY Trade
Cas No: 2483-46-7
No Data 10 Gram 2000 Metric Ton/Day Changchun JuShengyuan Import and Export Trading Co.,Ltd Contact Supplier

2483-46-7 Usage

Chemical Properties

Clear Oil

Uses

Nalpha, Nepsilon-Di-Boc-L-lysine is used as fine chemical intermediate, synthesis intermediates.
InChI:InChI=1/C16H30N2O6/c1-15(2,3)23-13(21)17-10-8-7-9-11(12(19)20)18-14(22)24-16(4,5)6/h11H,7-10H2,1-6H3,(H,17,21)(H,18,22)(H,19,20)

2483-46-7 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Alfa Aesar (H62019)  Nalpha,Nepsilon-Di-Boc-L-lysine, 98%    2483-46-7 25g 431.0CNY Detail
Alfa Aesar (H62019)  Nalpha,Nepsilon-Di-Boc-L-lysine, 98%    2483-46-7 100g 1294.0CNY Detail

2483-46-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2,6-bis[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid

1.2 Other means of identification

Product number -
Other names N2,N6-Bis[(1,1-dimethylethoxy)carbonyl]-L-lysine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2483-46-7 SDS

2483-46-7Synthetic route

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-Lysine hydrochloride
657-27-2, 10098-89-2

L-Lysine hydrochloride

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane; water at 20℃;100%
With sodium hydroxide In 1,4-dioxane; water at 10 - 20℃; for 20h; pH=7.05 - 10;92%
Stage #1: di-tert-butyl dicarbonate; L-Lysine hydrochloride With sodium hydrogencarbonate In tetrahydrofuran; water at 0 - 20℃; for 12h;
Stage #2: di-tert-butyl dicarbonate In tetrahydrofuran; water at 0 - 20℃; for 12h;
90%
N,N'-bis(tert-butyloxycarbonyl)-L-lysine dicyclohexylamine salt

N,N'-bis(tert-butyloxycarbonyl)-L-lysine dicyclohexylamine salt

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With potassium hydrogensulfate In diethyl ether; water for 0.333333h; Product distribution / selectivity;100%
With citric acid In water; ethyl acetate at 0℃; for 0.5h;97%
With water In ethyl acetate
With hydrogenchloride In water; ethyl acetate
L-lysine
56-87-1

L-lysine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane97%
With sodium hydrogencarbonate In tetrahydrofuran; water at 30℃; for 24h; Inert atmosphere;92%
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 12h;92%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

Boc-Lys-OH
13734-28-6

Boc-Lys-OH

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water for 18h; Cooling with ice;93%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-2-amino-6-(tert-butoxycarbonylamino)hexanoic acid
2418-95-3

(S)-2-amino-6-(tert-butoxycarbonylamino)hexanoic acid

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium hydroxide In water; tert-butyl alcohol at 20 - 40℃; for 16h;82%
Stage #1: di-tert-butyl dicarbonate; (S)-2-amino-6-(tert-butoxycarbonylamino)hexanoic acid With sodium hydroxide In tetrahydrofuran; water at 20℃; for 6h; pH=9 - 11;
Stage #2: With citric acid In water pH=4 - 5;
N-(tert-butyloxycarbonyl) azide
1070-19-5

N-(tert-butyloxycarbonyl) azide

L-Lysine hydrochloride
657-27-2, 10098-89-2

L-Lysine hydrochloride

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium carbonate
tert-butyl (quinolin-8-yl)carbonate
18595-55-6

tert-butyl (quinolin-8-yl)carbonate

L-lysine
56-87-1

L-lysine

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl-formamide
L-lysine
56-87-1

L-lysine

tert-Butyl 4-nitrophenyl carbonate
13303-10-1

tert-Butyl 4-nitrophenyl carbonate

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium hydroxide In tert-butyl alcohol
With triethylamine
1,1-dimethylethyl 2,4,5-trichlorophenyl carbonate
16965-08-5

1,1-dimethylethyl 2,4,5-trichlorophenyl carbonate

L-Lysine hydrochloride
657-27-2, 10098-89-2

L-Lysine hydrochloride

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With triethylamine In water; butan-1-ol
Nα,Nε-Di-tert.-butyloxycarbonyl-L-lysin-ethylester
99872-16-9

Nα,Nε-Di-tert.-butyloxycarbonyl-L-lysin-ethylester

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With sodium hydroxide
tert-Butyl 4-nitrophenyl carbonate
13303-10-1

tert-Butyl 4-nitrophenyl carbonate

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Py
2: aq. NaOH
View Scheme
L-lysine ethyl ester dihydrochloride
3844-53-9

L-lysine ethyl ester dihydrochloride

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Py
2: aq. NaOH
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
Stage #1: L-Lysine hydrochloride With water at 35℃;
Stage #2: di-tert-butyl dicarbonate With sodium hydroxide In water at 30 - 50℃; for 2h; pH=> 8;
Nα,Nε-di-Boc-L-lysine p-nitrophenyl ester
2592-19-0

Nα,Nε-di-Boc-L-lysine p-nitrophenyl ester

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Conditions
ConditionsYield
With Cu(II)(2,6-bis(6-monoamino-β-cyclodextrinmethyl)pyridine) In acetonitrile at 25℃; pH=8.2; Kinetics; Reagent/catalyst;
di(succinimido) carbonate
74124-79-1

di(succinimido) carbonate

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

N,N'-di-t-butyloxycarbonyl-(S)-lysine N-hydroxysuccinimide ester
30189-36-7

N,N'-di-t-butyloxycarbonyl-(S)-lysine N-hydroxysuccinimide ester

Conditions
ConditionsYield
With pyridine100%
2,3,4,5,6-pentafluorophenol
771-61-9

2,3,4,5,6-pentafluorophenol

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

pentafluorophenyl N-α-N-ε-di-Boc-L-lysinate
85535-59-7

pentafluorophenyl N-α-N-ε-di-Boc-L-lysinate

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In ethyl acetate at 20℃; for 1h;100%
With dicyclohexyl-carbodiimide In dichloromethane at 25℃;92%
With dicyclohexyl-carbodiimide In 1,4-dioxane for 2h;86.5%
With dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 1.75h;
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

N-hydroxysuccinimido diphenyl phosphate
75513-55-2

N-hydroxysuccinimido diphenyl phosphate

N,N'-di-t-butyloxycarbonyl-(S)-lysine N-hydroxysuccinimide ester
30189-36-7

N,N'-di-t-butyloxycarbonyl-(S)-lysine N-hydroxysuccinimide ester

Conditions
ConditionsYield
With pyridine100%
1,6-Hexanediamine
124-09-4

1,6-Hexanediamine

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Boc-L-Lys(Boc)-NH(CH2)6NH2

Boc-L-Lys(Boc)-NH(CH2)6NH2

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol at 20℃; for 1h; Acylation;100%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

[5-[6-(2,6-diamino-hexanoylamino)-hexylcarbamoyl]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-pentyl]-carbamic acid 9H-fluoren-9-ylmethyl ester

[5-[6-(2,6-diamino-hexanoylamino)-hexylcarbamoyl]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-pentyl]-carbamic acid 9H-fluoren-9-ylmethyl ester

[5-{6-[2,6-bis-(2,6-bis-tert-butoxycarbonylamino-hexanoylamino)-hexanoylamino]-hexylcarbamoyl}-5-(9H-fluoren-9-ylmethoxycarbonylamino)-pentyl]-carbamic acid 9H-fluoren-9-ylmethyl ester

[5-{6-[2,6-bis-(2,6-bis-tert-butoxycarbonylamino-hexanoylamino)-hexanoylamino]-hexylcarbamoyl}-5-(9H-fluoren-9-ylmethoxycarbonylamino)-pentyl]-carbamic acid 9H-fluoren-9-ylmethyl ester

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; benzotriazol-1-ol at 20℃; for 1h; Acylation;100%
(S)-methyl 2-amino-6-(tert-butoxycarbonylamino)hexanoate
3017-32-1

(S)-methyl 2-amino-6-(tert-butoxycarbonylamino)hexanoate

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Boc-Lys(Boc)-Lys(Boc)-OMe

Boc-Lys(Boc)-Lys(Boc)-OMe

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2.5h;100%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

C60H93N9O14S

C60H93N9O14S

C76H121N11O19S

C76H121N11O19S

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 0 - 20℃;100%
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 0 - 20℃;0.270 g
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

L-lysine dihydrochloride
657-26-1

L-lysine dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane; methanol at 20℃; for 24h;100%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

2,6-Dichlor-N-phenylbenzimidchlorid
113055-87-1

2,6-Dichlor-N-phenylbenzimidchlorid

Nα,Nε-Bis(tert-butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenyl-L-lysinamid
113035-36-2

Nα,Nε-Bis(tert-butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenyl-L-lysinamid

Conditions
ConditionsYield
With triethylamine In acetone for 4h; Ambient temperature;99%
1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

N,N'-di-t-butyloxycarbonyl-(S)-lysine N-hydroxysuccinimide ester
30189-36-7

N,N'-di-t-butyloxycarbonyl-(S)-lysine N-hydroxysuccinimide ester

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;99%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃;88%
With dicyclohexyl-carbodiimide In tetrahydrofuran86%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

C20H29ClN4O2*2C2HF3O2

C20H29ClN4O2*2C2HF3O2

C36H57ClN6O7

C36H57ClN6O7

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 14.5h; Inert atmosphere;99%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

N-decyl-1-aminomethylnaphthalene hydrochloride
1558953-12-0

N-decyl-1-aminomethylnaphthalene hydrochloride

1-(N-(Nα,Nε-di-Boc-Lys)-N-decylamino)methylnaphthalene
1558953-40-4

1-(N-(Nα,Nε-di-Boc-Lys)-N-decylamino)methylnaphthalene

Conditions
ConditionsYield
Stage #1: Boc-Lys(Boc)-OH With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: N-decyl-1-aminomethylnaphthalene hydrochloride In chloroform; N,N-dimethyl-formamide at 0 - 20℃; for 24.5h;
98%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

(S)-2-amino-N-methoxy-N-methylpropanamide hydrochloride

(S)-2-amino-N-methoxy-N-methylpropanamide hydrochloride

di-tert-butyl ((S)-6-(((S)-1-(methoxy(methyl)amino)-1-oxopropan-2-yl)amino)-6-oxohexane-1,5-diyl)dicarbamate

di-tert-butyl ((S)-6-(((S)-1-(methoxy(methyl)amino)-1-oxopropan-2-yl)amino)-6-oxohexane-1,5-diyl)dicarbamate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1.5h; Inert atmosphere;98%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

methyl iodide
74-88-4

methyl iodide

(+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester
2483-48-9

(+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester

Conditions
ConditionsYield
With potassium carbonate In ethyl acetate; N,N-dimethyl-formamide at 10 - 20℃; for 5h; Inert atmosphere;97%
Stage #1: Boc-Lys(Boc)-OH With caesium carbonate In tetrahydrofuran; water
Stage #2: methyl iodide In N,N-dimethyl-formamide for 2h;
65%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;3 g
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

N-hexyl-1-aminomethylbenzene hydrochloride
90389-37-0

N-hexyl-1-aminomethylbenzene hydrochloride

1-(N-(Nα,Nε-di-Boc-Lys)-N-hexylamino)methylbenzene
1558953-46-0

1-(N-(Nα,Nε-di-Boc-Lys)-N-hexylamino)methylbenzene

Conditions
ConditionsYield
Stage #1: Boc-Lys(Boc)-OH With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: N-hexyl-1-aminomethylbenzene hydrochloride In chloroform; N,N-dimethyl-formamide at 0 - 20℃; for 24.5h;
97%
Stage #1: Boc-Lys(Boc)-OH With N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide
Stage #2: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate In chloroform; N,N-dimethyl-formamide
Stage #3: N-hexyl-1-aminomethylbenzene hydrochloride In chloroform; N,N-dimethyl-formamide at 0 - 20℃; for 24.5h;
beta-alanine methyl ester hydrochloride

beta-alanine methyl ester hydrochloride

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

(S)-methyl 3-(2,6-bis(tert-butoxycarbonylamino)hexanamido)propanoate

(S)-methyl 3-(2,6-bis(tert-butoxycarbonylamino)hexanamido)propanoate

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide97%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

methyl 3-aminopropanoate hydrochloride
3196-73-4

methyl 3-aminopropanoate hydrochloride

(S)-methyl 3-(2,6-bis(tert-butoxycarbonylamino)hexanamido)propanoate

(S)-methyl 3-(2,6-bis(tert-butoxycarbonylamino)hexanamido)propanoate

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide97%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

(S)-3-(3-fluoro-4-morpholinophenyl)-5-((octylamino)methyl)oxazolidin-2-one

(S)-3-(3-fluoro-4-morpholinophenyl)-5-((octylamino)methyl)oxazolidin-2-one

di-tert-butyl ((5s)-6-(((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl) (octyl)amino)-6-oxohexane-1,5-diyl)dicarbamate

di-tert-butyl ((5s)-6-(((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl) (octyl)amino)-6-oxohexane-1,5-diyl)dicarbamate

Conditions
ConditionsYield
Stage #1: (S)-3-(3-fluoro-4-morpholinophenyl)-5-((octylamino)methyl)oxazolidin-2-one With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: Boc-Lys(Boc)-OH In chloroform; N,N-dimethyl-formamide at 0 - 20℃; for 24.5h;
96.9%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

(S)-5-((decylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

(S)-5-((decylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

di-tert-butyl ((5s)-6-(decyl((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)amino)-6-oxohexane-1,5-diyl)dicarbamate

di-tert-butyl ((5s)-6-(decyl((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)amino)-6-oxohexane-1,5-diyl)dicarbamate

Conditions
ConditionsYield
Stage #1: (S)-5-((decylamino)methyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: Boc-Lys(Boc)-OH In chloroform; N,N-dimethyl-formamide at 0 - 20℃; for 24.5h;
96.7%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

1-aminooctadecane
124-30-1

1-aminooctadecane

((S)-5-tert-Butoxycarbonylamino-5-octadecylcarbamoyl-pentyl)-carbamic acid tert-butyl ester

((S)-5-tert-Butoxycarbonylamino-5-octadecylcarbamoyl-pentyl)-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 24h; Inert atmosphere;96%
With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In chloroform at 0℃;
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

[5-tert-butoxycarbonylamino-5-(methoxy-methyl-carbamoyl)-pentyl]-carbamic acid tert-butyl ester
761456-85-3

[5-tert-butoxycarbonylamino-5-(methoxy-methyl-carbamoyl)-pentyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: Boc-Lys(Boc)-OH With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 0.25h; Inert atmosphere;
Stage #2: N,O-dimethylhydroxylamine*hydrochloride With 4-methyl-morpholine In dichloromethane at 0 - 25℃; for 14h; Inert atmosphere;
96%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 1h;94%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

methyl 6-O-trityl-α-D-glucopyranoside
18311-26-7

methyl 6-O-trityl-α-D-glucopyranoside

methyl 2,3,4-tri-O-α,Nε-bis(t-butoxycarbonyl)-L-lysyl>-6-O-triphenylmethyl-α-D-glucopyranoside

methyl 2,3,4-tri-O-α,Nε-bis(t-butoxycarbonyl)-L-lysyl>-6-O-triphenylmethyl-α-D-glucopyranoside

Conditions
ConditionsYield
With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane 1) 0 deg C, 2 h, 2) r.t., overnight;95%
C35H63N11O14
192873-60-2

C35H63N11O14

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

C51H91N13O19
1402052-18-9

C51H91N13O19

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Inert atmosphere;95%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

C94H167ClN6O19Si4

C94H167ClN6O19Si4

C110H195ClN8O24Si4

C110H195ClN8O24Si4

Conditions
ConditionsYield
Stage #1: Boc-Lys(Boc)-OH With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.25h;
Stage #2: C94H167ClN6O19Si4 In N,N-dimethyl-formamide at 0 - 20℃;
95%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

C17H41N9O2

C17H41N9O2

C41H89N17O6

C41H89N17O6

Conditions
ConditionsYield
Stage #1: Boc-Lys(Boc)-OH; C17H41N9O2 With diisopropyl-carbodiimide In methanol at 20℃; for 0.25h;
Stage #2: With trifluoroacetic acid In methanol; dichloromethane for 2h;
95%
(1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid dimethyl ester hydrochloride

(1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid dimethyl ester hydrochloride

Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

(1S,2S,5R,6S)-2-[(2'S)-(2',6'-bis(tert-butoxycarbonyl)amino)hexanoyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid dimethyl ester
441775-51-5

(1S,2S,5R,6S)-2-[(2'S)-(2',6'-bis(tert-butoxycarbonyl)amino)hexanoyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With dmap; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine In dichloromethane at 20℃;94%
Boc-Lys(Boc)-OH
2483-46-7

Boc-Lys(Boc)-OH

Propargylamine
2450-71-7

Propargylamine

(S)-di-(tert-butyl) 6-oxo-6-(prop-2-ynylamino)hexane-1,5-diyldicarbamate
478843-83-3

(S)-di-(tert-butyl) 6-oxo-6-(prop-2-ynylamino)hexane-1,5-diyldicarbamate

Conditions
ConditionsYield
Stage #1: Boc-Lys(Boc)-OH With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In dichloromethane for 0.166667h; Cooling with ice;
Stage #2: Propargylamine With triethylamine In dichloromethane
94%
Stage #1: Boc-Lys(Boc)-OH With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 0.5h;
Stage #2: Propargylamine With triethylamine In dichloromethane at 0℃;
94%
With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24.5h; Inert atmosphere; Cooling with ice;64%
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 2483-46-7