2',4'-DIFLUORO-3-PHENYLPROPIOPHENONE

Base Information

• Chemical Name: 2',4'-DIFLUORO-3-PHENYLPROPIOPHENONE
• CAS No.: 898788-87-9
• Molecular Formula: C15H12F2O
• Molecular Weight: 246.256
• Hs Code.: 2914700090
• Mol file: 898788-87-9.mol

Synonyms:2,4-DIFLUORO-3-PHENYLPROPIOPHENONE

Chemical Property of 2',4'-DIFLUORO-3-PHENYLPROPIOPHENONE

Chemical Property:

• Vapor Pressure: 2.35E-05mmHg at 25°C
• Boiling Point: 359.6°C at 760 mmHg
• Flash Point: 137.6°C
• PSA: 17.07000
• Density: 1.191g/cm³
• LogP: 3.78030

Purity/Quality:

97% ^*data from raw suppliers

2',4'-difluoro-3-phenylpropiophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2',4'-DIFLUORO-3-PHENYLPROPIOPHENONE

There total 4 articles about 2',4'-DIFLUORO-3-PHENYLPROPIOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-1-(2,4-difluorophenyl)-3-phenylprop-2-en-1-one → 1-(2,4-difluoro-phenyl)-3-phenyl-propan-1-one (898788-87-9)

Guidance literature:

With formic acid; tributyl-amine; palladium on activated charcoal; at 100 ℃; for 10h;

Reference yield:

2',4'-difluoroacetophenone (364-83-0) → 1-(2,4-difluoro-phenyl)-3-phenyl-propan-1-one (898788-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / 20 °C

2: formic acid; tributylamine / Pd/C / 10 h / 100 °C

With sodium hydroxide; formic acid; tributyl-amine; palladium on activated charcoal; In ethanol;

Reference yield:

benzaldehyde (100-52-7) → 1-(2,4-difluoro-phenyl)-3-phenyl-propan-1-one (898788-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / 20 °C

2: formic acid; tributylamine / Pd/C / 10 h / 100 °C

With sodium hydroxide; formic acid; tributyl-amine; palladium on activated charcoal; In ethanol;

upstream raw materials:

2',4'-difluoroacetophenone

benzaldehyde

Downstream raw materials:

5-benzyl-4-(2,4-difluorophenyl)thiazol-2-amine

C₁₅H₁₁BrF₂O

5-benzyl-4-(2,4-difluorophenyl)-N-(4-methoxybenzyl)thiazol-2-amine