1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)-

Base Information

Chemical Name:1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)-
CAS No.:86523-76-4
Molecular Formula:C18H23N5O
Molecular Weight:325.414
Hs Code.:
DSSTox Substance ID:DTXSID90235627
Nikkaji Number:J564.985D
Wikidata:Q83117505
ChEMBL ID:CHEMBL53615

Synonyms:BRN 5621920;1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)-;N-(4-Aminophenyl)-4-(2-pyridinyl)-1-piperazinepropanamide;86523-76-4;CHEMBL53615;SCHEMBL11002259;DTXSID90235627;LS-113166;3-[4-(2-Pyridyl)piperazin-1-yl]-N-(4-aminophenyl)propanamide

Suppliers and Price of 1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)-

Chemical Property:

Vapor Pressure:3.27E-11mmHg at 25°C
Boiling Point:527.4°Cat760mmHg
Flash Point:272.8°C
Density:1.235g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:325.19026037
Heavy Atom Count:24
Complexity:389

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CCC(=O)NC2=CC=C(C=C2)N)C3=CC=CC=N3

Technology Process of 1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)-

There total 4 articles about 1-Piperazinepropanamide, N-(4-aminophenyl)-4-(2-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 86523-75-3
N-(4-Nitro-phenyl)-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

: 86523-76-4
N-(4-aminophenyl)-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 3102.9 Torr;
DOI:10.1021/jm00384a002

Reference yield:

: 7766-38-3
N-(4-nitrophenyl) acrylamide

: 86523-76-4
N-(4-aminophenyl)-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / toluene / 6 h / Heating

2: 60 percent / H₂ / Pd/C / methanol

With hydrogen; palladium on activated charcoal; In methanol; toluene;
DOI:10.1016/0223-5234(93)90117-W

Reference yield:

: 34803-66-2
1-(2-pyridyl)piperazine

: 86523-76-4
N-(4-aminophenyl)-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / benzene / Heating

2: 73 percent / H₂ / 10percent Pd/C / methanol / 3102.9 Torr

With hydrogen; palladium on activated charcoal; In methanol; benzene;
DOI:10.1021/jm00384a002