4-Pyrimidinemethanol, 2-methoxy- (9CI)

Base Information

Chemical Name:4-Pyrimidinemethanol, 2-methoxy- (9CI)
CAS No.:38696-25-2
Molecular Formula:C6H8N2O2
Molecular Weight:140.14
Hs Code.:2933599090
Mol file:38696-25-2.mol

Synonyms:(2-Methoxypyrimidin-4-yl)methanol;

Suppliers and Price of 4-Pyrimidinemethanol, 2-methoxy- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2-Methoxypyrimidin-4-yl)methanol
50mg
$ 155.00

Matrix Scientific
4-Hydroxymethyl-2-methoxypyrimidine 90+%
1g
$ 1073.00

Chemenu
4-Pyrimidinemethanol,2-methoxy- 95%
1g
$ 677.00

ACHEMBLOCK
(2-Methoxypyrimidin-4-yl)methanol 97%
1G
$ 585.00

ACHEMBLOCK
(2-Methoxypyrimidin-4-yl)methanol 97%
250MG
$ 195.00

Total 10 raw suppliers

Chemical Property of 4-Pyrimidinemethanol, 2-methoxy- (9CI)

Chemical Property:

Boiling Point:303.964 °C at 760 mmHg
PKA:13.15±0.10(Predicted)
Flash Point:137.633 °C
PSA：55.24000
Density:1.233 g/cm³
LogP:-0.02250

Purity/Quality:

97% ^*data from raw suppliers

(2-Methoxypyrimidin-4-yl)methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Pyrimidinemethanol, 2-methoxy- (9CI)

There total 4 articles about 4-Pyrimidinemethanol, 2-methoxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 124-41-4
sodium methylate

: 102921-92-6
4-(hydroxymethyl)-2-(methylthio)pyrimidine

: 38696-25-2
4-(hydroxymethyl)-2-methoxypyrimidine

Guidance literature:: In methanol; for 12h; Heating;
DOI:10.1021/jm00158a009

Reference yield:

: 50593-92-5
5-bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid

: 38696-25-2
4-(hydroxymethyl)-2-methoxypyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / KOH, H₂ / 5percent Pd/BaSO₄ / methanol / 1810.02 Torr

2: 68 percent / N,N-dimethylchloromethyleniminium chloride, NaBH₄ / CH₂Cl₂; tetrahydrofuran; acetonitrile; dimethylformamide / 3 h / -78 - -20 °C

3: 71 percent / methanol / 12 h / Heating

With potassium hydroxide; sodium tetrahydroborate; N,N-dimethylchloromethyleniminium chloride; hydrogen; Pd-BaSO₄; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00158a009

Reference yield:

: 1126-44-9
2-methylsulfanylpyrimidine-4-carboxylic acid

: 38696-25-2
4-(hydroxymethyl)-2-methoxypyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / N,N-dimethylchloromethyleniminium chloride, NaBH₄ / CH₂Cl₂; tetrahydrofuran; acetonitrile; dimethylformamide / 3 h / -78 - -20 °C

2: 71 percent / methanol / 12 h / Heating

With sodium tetrahydroborate; N,N-dimethylchloromethyleniminium chloride; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00158a009