7-Chloro-5-methoxythieno[3,2-b]pyridine

Base Information

Chemical Name:7-Chloro-5-methoxythieno[3,2-b]pyridine
CAS No.:74695-46-8
Molecular Formula:C₈H₆ClNOS
Molecular Weight:199.661
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00504912
Wikidata:Q72453546
Mol file:74695-46-8.mol

Synonyms:7-Chloro-5-methoxythieno[3,2-b]pyridine;74695-46-8;DTXSID00504912;ZCA69546;MFCD12755908;AKOS016005421;AB65849;AS-63976;CS-0061954;W16906;EN300-1601902

Suppliers and Price of 7-Chloro-5-methoxythieno[3,2-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-Chloro-5-methoxythieno[3,2-b]pyridine 95+%
1g
$ 515.00

ChemScene
7-chloro-5-methoxythieno[3,2-b]pyridine
1g
$ 780.00

ChemScene
7-chloro-5-methoxythieno[3,2-b]pyridine
250mg
$ 390.00

ChemScene
7-chloro-5-methoxythieno[3,2-b]pyridine
100mg
$ 234.00

American Custom Chemicals Corporation
7-CHLORO-5-METHOXYTHIENO[3,2-B]PYRIDINE 95.00%
5MG
$ 496.54

Alichem
7-Chloro-5-methoxythieno[3,2-b]pyridine
1g
$ 453.44

AK Scientific
7-Chloro-5-methoxythieno[3,2-b]pyridine
1g
$ 668.00

AK Scientific
7-Chloro-5-methoxythieno[3,2-b]pyridine
100mg
$ 205.00

Total 15 raw suppliers

Chemical Property of 7-Chloro-5-methoxythieno[3,2-b]pyridine

Chemical Property:

Melting Point:97-98 oC
Boiling Point:277 oC
Flash Point:121 oC
PSA：50.36000
Density:1.404
LogP:2.95830
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:198.9858627
Heavy Atom Count:12
Complexity:169

Purity/Quality:

98%min ^*data from raw suppliers

7-Chloro-5-methoxythieno[3,2-b]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NC2=C(C(=C1)Cl)SC=C2

Technology Process of 7-Chloro-5-methoxythieno[3,2-b]pyridine

There total 7 articles about 7-Chloro-5-methoxythieno[3,2-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 124-41-4
sodium methylate

: 74695-44-6
5,7-dichlorothieno<3,2-b>pyridine

: 74695-46-8
7-chloro-5-methoxythieno<3,2-b>pyridine

Guidance literature:: In methanol; for 2h; Heating;

Reference yield: 81.0%

: 124-41-4
sodium methylate

: 74695-44-6
5,7-dichlorothieno<3,2-b>pyridine

: 74695-46-8
7-chloro-5-methoxythieno<3,2-b>pyridine

: 90690-91-8
5-chloro-7-methoxythieno<3,2-b>pyridine

Guidance literature:: With 15-crown-5;
DOI:10.1016/j.bmcl.2004.05.070

Reference yield:

: 31823-64-0
methyl 3-amino-2-thiophenecarboxylate

: 74695-46-8
7-chloro-5-methoxythieno<3,2-b>pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / 1.5 h / Heating

2: 73 percent / NaOEt / ethanol / 8 h / Heating

3: 1) 20percent aq. NaOH, 2) conc. HCl / 1) heating, 2 h, 2) heating

4: 9 percent / POCl₃ / 3 h / Heating

5: diethyl ether

With hydrogenchloride; sodium hydroxide; sodium ethanolate; trichlorophosphate; In diethyl ether; ethanol;