31823-64-0

Usage

Chemical Properties

White crystal

Upstream product

• 623-51-8 ethyl 2-sulfanylacetate 
• 920-37-6 2-Chloroacrylonitrile 

Downstream Products

• 875570-35-7 3-allyloxy-1H-thieno[3,2-d]pyrimidine-2,4-dione 
• 16234-10-9 3H-thieno[3,2-d]pyrimidin-4-one 
• 137844-98-5 3-aminothiophene-2-carbohydrazide 
• 1262031-37-7 C₁₅H₁₅NO₃S 
• 62224-14-0 ethyl ester of 3-bromo-2-thiophenecarboxylic acid 
• 74695-37-7 6-acetyl-7-hydroxythieno<3,2-b>pyridin-5(4H)-one 
• 74695-46-8 7-chloro-5-methoxythieno<3,2-b>pyridine 
• 74695-44-6 5,7-dichlorothieno<3,2-b>pyridine 
• 74695-45-7 7-chlorothieno<3,2-b>pyridin-5(4H)-one 
• 74695-40-2 7-hydroxythieno<2,3-b>pyridin-5(4H)-one 

Relevant academic research and scientific papers

Synthesis of a novel series of thieno[3,2-d]pyrimidin-4-(3H)-ones

2-Aminothieno[3,2-d]pyrimidin-4-ones were synthesized in one step by condensation of 3-amino(benzo)thiophene car-boxylate with chloroformamidine hydrochloride. Georg Thieme Verlag Stuttgart.

1,2-Dithiolan-3-ones and derivatives structurally related to leinamycin. Synthesis and biological evaluation

Leinamycin, an antitumor antibiotic isolated from Streptomyces sp., shows a 1,2-dithiolan-3-one 1-oxide heterocycle that appears to be involved in the biological activity. Several derivatives related to 1,2-dithiolan-3-one 1-oxide have been prepared and their activity as antineoplastic agents have been investigated. The synthesized compounds did not display a significative antitumor or cytotoxic activity in vitro.

Synthesis of 3H-Thieno-1,2-dithiole-3-thione and its Reaction with n-Butylamine

A convenient synthesis of 3H-thieno-1,2-dithiole-3-thione (7) is proposed.The reaction of 7 with n-butylamine afforded the N-butylthienoisothiazole-3(2H)-thione (7a) in dynamically equilibrium with its 3H-thieno-1,2-dithiole-N-butyl-3-imino isomer 7b.Characterizations and antimicrobial activities of the synthesized products are reported.