2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE

Base Information

• Chemical Name: 2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE
• CAS No.: 929302-18-1
• Molecular Formula: C12H22N2O2.ClH
• Molecular Weight: 262.78
• Hs Code.: 2933990090
• Mol file: 929302-18-1.mol

Synonyms:2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE;2-Methyl-2,7-diaza-spiro[3.5]nonane;tert-butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate hydrochloride;2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 1,1-diMethylethyl ester, (Hydrochloride) (1:1);2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 1,1-diMethylethyl ester, hydrochloride

Chemical Property of 2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0952mmHg at 25°C
• Boiling Point: 223.6°C at 760 mmHg
• Flash Point: 98.4°C
• PSA: 15.27000
• Density: 1.01g/cm³
• LogP: 0.56830
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl2,7-diazaspiro[3.5]nonane-2-carboxylatehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE

There total 1 articles about 2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 7-benzyl-2,7-diazaspiro[3.5]nonane-2-carboxylate (929301-99-5) → 2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-ium hydrochloride (929302-18-1)

Guidance literature:

tert-butyl 7-benzyl-2,7-diazaspiro[3.5]nonane-2-carboxylate; With hydrogen; palladium dihydroxide; In methanol; at 35 ℃; under 2844.39 Torr;

With hydrogenchloride; In methanol; diethyl ether; pH=6 - 7;

Reference yield:

2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-ium hydrochloride (929302-18-1) + C22H18BrCl2FN4O2 → C34H39BrClFN6O4

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 16h;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-ium hydrochloride (929302-18-1) → 7-methyl-2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester (1093066-77-3)

Guidance literature:

formaldehyd; 2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-ium hydrochloride; In water; 1,2-dichloro-ethane; at 20 ℃; for 0.166667h;

With sodium tris(acetoxy)borohydride; In water; 1,2-dichloro-ethane; for 1h;

With ammonia; In methanol;

upstream raw materials:

tert-butyl 7-benzyl-2,7-diazaspiro[3.5]nonane-2-carboxylate

Downstream raw materials:

7-methyl-2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester

7-methyl-2,7-diazaspiro<3.5>-nonane

Refernces