2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester

Base Information

Chemical Name:2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester
CAS No.:1093066-77-3
Molecular Formula:C₁₃H₂₄N₂O₂
Molecular Weight:240.346
Hs Code.:
Mol file:1093066-77-3.mol

Synonyms:2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester

Suppliers and Price of 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 5 raw suppliers

Chemical Property of 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester

Chemical Property:

PSA：32.78000
LogP:1.82490

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester

There total 3 articles about 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 929302-18-1
2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-ium hydrochloride

: 1093066-77-3
7-methyl-2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester

Guidance literature:: formaldehyd; 2-(tert-butoxycarbonyl)-2,7-diazaspiro[3.5]nonan-7-ium hydrochloride; In water; 1,2-dichloro-ethane; at 20 ℃; for 0.166667h;

With sodium tris(acetoxy)borohydride; In water; 1,2-dichloro-ethane; for 1h;

With ammonia; In methanol;

Reference yield:

: 236406-55-6
2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1093066-77-3
7-methyl-2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester

Guidance literature:: 2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester; formaldehyd; In tetrahydrofuran; water; for 0.5h;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; water; at 20 ℃;

Reference yield:

: 929301-99-5
tert-butyl 7-benzyl-2,7-diazaspiro[3.5]nonane-2-carboxylate

: 1093066-77-3
7-methyl-2,7-diaza-spiro[3.5]nonane-2-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium 10% on activated carbon; hydrogen / methanol / 96 h / 0 - 20 °C / 760.05 Torr

2.1: tetrahydrofuran; water / 0.5 h

2.2: 20 °C

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; water;