4-(quinoliN-8-yl)phenylbornic acid,pinacol ester

Base Information

Chemical Name:4-(quinoliN-8-yl)phenylbornic acid,pinacol ester
CAS No.:1233131-18-4
Molecular Formula:C21H22BNO2
Molecular Weight:331.222
Hs Code.:
Mol file:1233131-18-4.mol

Synonyms:4-(quinoliN-8-yl)phenylbornic acid,picol ester;4-(quinoliN-8-yl)phenylbornic acid,pinacol ester;4-(quinolin-8-yl)phenylboronic acid, pinacol ester;8-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]quinoline;Quinoline, 8-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-

Suppliers and Price of 4-(quinoliN-8-yl)phenylbornic acid,pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 21 raw suppliers

Chemical Property of 4-(quinoliN-8-yl)phenylbornic acid,pinacol ester

Chemical Property:

Boiling Point:464.0±33.0 °C(Predicted)
PKA:4.24±0.17(Predicted)
PSA：31.35000
Density:1.14±0.1 g/cm3(Predicted)
LogP:4.20100

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(quinoliN-8-yl)phenylbornic acid,pinacol ester

There total 3 articles about 4-(quinoliN-8-yl)phenylbornic acid,pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1393817-78-1
8-(4-bromophenyl)quinoline

: 73183-34-3
bis(pinacol)diborane

: 1233131-18-4
8-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)quinoline

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In 1,4-dioxane; at 100 ℃; for 3h; Inert atmosphere;

Reference yield:

: 86-58-8
8-quinolinylboronic acid

: 1233131-18-4
8-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; palladium diacetate; potassium phosphate / toluene; water; ethanol / 15 h / 74 °C / Inert atmosphere

2: potassium acetate; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 3 h / 100 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; potassium acetate; palladium diacetate; triphenylphosphine; In 1,4-dioxane; ethanol; water; toluene;

Reference yield:

: 589-87-7
1,4-bromoiodobenzene

: 1233131-18-4
8-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; palladium diacetate; potassium phosphate / toluene; water; ethanol / 15 h / 74 °C / Inert atmosphere

2: potassium acetate; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 3 h / 100 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; potassium acetate; palladium diacetate; triphenylphosphine; In 1,4-dioxane; ethanol; water; toluene;