Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate

Base Information

• Chemical Name: Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate
• CAS No.: 886366-37-6
• Molecular Formula: C₁₂H₁₀FNO₂S
• Molecular Weight: 251.281
• Mol file: 886366-37-6.mol

Synonyms:Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate

Chemical Property of Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate

Chemical Property:

• PSA: 67.43000
• LogP: 3.12590

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-(4-fluorophenyl)thiazole-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate

There total 1 articles about Ethyl 4-(4-Fluorophenyl)-2-thiazolecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.01%

ethyl 2-amino-2-thioxoacetate (16982-21-1) + 2-bromo-4'-fluoroacetophenone (403-29-2) → ethyl 4-(4-fluorophenyl)thiazole-2-carboxylate (886366-37-6)

Guidance literature:

In ethanol; at 80 ℃; for 6h;

DOI:10.1016/j.bmc.2021.116370

upstream raw materials:

ethyl 2-amino-2-thioxoacetate

2-bromo-4'-fluoroacetophenone