1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethane-1,2-dione

Base Information

Chemical Name:1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethane-1,2-dione
CAS No.:356560-76-4
Molecular Formula:C15H11NO4
Molecular Weight:269.257
Hs Code.:
Mol file:356560-76-4.mol

Synonyms:1-Benzo[1,3]dioxol-5-yl-2-(6-methyl-pyridin-2-yl)-ethane-1,2-dione;1-(1,3-Benzodioxol-5-yl)-2-(6-methyl-2-pyridinyl)-1,2-ethanedione;

Suppliers and Price of 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethane-1,2-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethane-1,2-dione

Chemical Property:

PSA：65.49000
LogP:2.18430

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethane-1,2-dione

There total 4 articles about 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethane-1,2-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 356560-89-9
1-(benzo[1,3]dioxol-5-yl)-2-(6-methylpyridin-2-yl)ethanone

: 356560-76-4
1-(benzo[1,3]dioxol-5-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

Guidance literature:: With hydrogen bromide; dimethyl sulfoxide; at 60 - 70 ℃; for 2h;
DOI:10.1021/jm070129k

Reference yield:

: 108-48-5
2,6-dimethylpyridine

: 356560-76-4
1-(benzo[1,3]dioxol-5-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium bis(trimethylsilyl)amide / tetrahydrofuran / -60 °C

1.2: 76 percent / tetrahydrofuran / 0.33 h / -60 °C

2.1: 92 percent / DMSO; aq. HBr / 2 h / 60 - 70 °C

With hydrogen bromide; dimethyl sulfoxide; lithium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1021/jm070129k

Reference yield:

: 326-56-7
methyl 3,4-methylenedioxybenzoate

: 356560-76-4
1-(benzo[1,3]dioxol-5-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium bis(trimethylsilyl)amide / tetrahydrofuran / -60 °C

1.2: 76 percent / tetrahydrofuran / 0.33 h / -60 °C

2.1: 92 percent / DMSO; aq. HBr / 2 h / 60 - 70 °C

With hydrogen bromide; dimethyl sulfoxide; lithium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1021/jm070129k