1,5-Naphthyridin-3-amine

Base Information

Chemical Name:1,5-Naphthyridin-3-amine
CAS No.:14756-77-5
Molecular Formula:C8H7N3
Molecular Weight:145.16
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10343374
Nikkaji Number:J81.798H
Wikidata:Q72439921
Mol file:14756-77-5.mol

Synonyms:1,5-Naphthyridin-3-amine;14756-77-5;3-amino-1,5-naphthyridine;1,5-Naphthyridine, 3-amino-;[1,5]NAPHTHYRIDIN-3-YLAMINE;SCHEMBL2714994;DTXSID10343374;AMY26004;MFCD13189455;AKOS005135732;AB68450;GS-5970;1,5-Naphthyridin-3-amine, AldrichCPR;FT-0682872;EN300-239561;A928613;F1957-0120

Suppliers and Price of 1,5-Naphthyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,5-Naphthyridin-3-amine
50mg
$ 130.00

Sigma-Aldrich
1,5-Naphthyridin-3-amine Aldrich
1g
$ 802.00

Matrix Scientific
1,5-Naphthyridin-3-amine
1g
$ 614.00

Matrix Scientific
1,5-Naphthyridin-3-amine
250mg
$ 260.00

Matrix Scientific
1,5-Naphthyridin-3-amine
500mg
$ 400.00

Crysdot
1,5-Naphthyridin-3-amine 95+%
1g
$ 608.00

American Custom Chemicals Corporation
1,5-NAPHTHYRIDIN-3-AMINE 95.00%
250MG
$ 1033.73

Ambeed
1,5-Naphthyridin-3-amine 98%
250mg
$ 175.00

Ambeed
1,5-Naphthyridin-3-amine 98%
100mg
$ 109.00

Ambeed
1,5-Naphthyridin-3-amine 98%
1g
$ 442.00

Total 23 raw suppliers

Chemical Property of 1,5-Naphthyridin-3-amine

Chemical Property:

Melting Point:144-145 °C(Solv: ligroine (8032-32-4))
Boiling Point:329.7±22.0 °C(Predicted)
PKA:3.08±0.10(Predicted)
PSA：51.80000
Density:1.292±0.06 g/cm3(Predicted)
LogP:1.79320
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:145.063997236
Heavy Atom Count:11
Complexity:137

Purity/Quality:

97% ^*data from raw suppliers

1,5-Naphthyridin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C(C=N2)N)N=C1

Technology Process of 1,5-Naphthyridin-3-amine

There total 7 articles about 1,5-Naphthyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 959617-73-3
tert-butyl (1,5-naphthyridin-3-yl)carbamate

: 14756-77-5
3-Amino-1,5-naphthyridin

Guidance literature:: With hydrogenchloride; water; In methanol; at 50 ℃; for 2h;

Reference yield:

: 254-79-5
1,5-naphthyridine

: 14756-77-5
3-Amino-1,5-naphthyridin

Guidance literature:: Multi-step reaction with 3 steps

1: sodium acetate; bromine / acetic acid / 2 h / 80 - 90 °C

2: caesium carbonate / 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 16 h / Reflux; Inert atmosphere

3: hydrogenchloride; water / methanol / 2 h / 50 °C

With hydrogenchloride; water; bromine; sodium acetate; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; methanol; acetic acid;

Reference yield:

: 17965-71-8
3-bromo-1,5-naphthyridine

: 14756-77-5
3-Amino-1,5-naphthyridin

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 16 h / Reflux; Inert atmosphere

2: hydrogenchloride; water / methanol / 2 h / 50 °C

With hydrogenchloride; water; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; methanol;