5-bromo-7-fluoro-1H-indole

Base Information

Chemical Name:5-bromo-7-fluoro-1H-indole
CAS No.:883500-73-0
Molecular Formula:C8H5BrFN
Molecular Weight:214.037
Hs Code.:2933990090
European Community (EC) Number:694-420-7
DSSTox Substance ID:DTXSID70393416
Wikidata:Q72456044
Mol file:883500-73-0.mol

Synonyms:5-bromo-7-fluoro-1H-indole;5-Bromo-7-fluoroindole;883500-73-0;MFCD04037876;SCHEMBL120501;5-Bromo-7-fluoroindole, 97%;AMY7585;DTXSID70393416;TZRRRWOVYVGRSL-UHFFFAOYSA-N;BBL101489;STL555285;AKOS005259074;PB10286;AC-29667;CS-11232;SY011170;BB 0261256;CS-0037549;FT-0677004;EN300-108553;P10285;A862233

Suppliers and Price of 5-bromo-7-fluoro-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-7-fluoro-1H-indole
100mg
$ 110.00

SynQuest Laboratories
5-Bromo-7-fluoro-1H-indole
1 g
$ 360.00

Sigma-Aldrich
5-Bromo-7-fluoroindole 97%
500mg
$ 92.70

Matrix Scientific
5-Bromo-7-fluoroindole 95%
5g
$ 1100.00

Matrix Scientific
5-Bromo-7-fluoroindole 95%
1g
$ 300.00

Matrix Scientific
5-Bromo-7-fluoroindole 95%
250mg
$ 128.00

J&W Pharmlab
5-Bromo-7-fluoro-1H-indole 96%
1g
$ 178.00

J&W Pharmlab
5-Bromo-7-fluoro-1H-indole 96%
5g
$ 598.00

J&W Pharmlab
5-Bromo-7-fluoro-1H-indole 96%
25g
$ 1998.00

J&W Pharmlab
5-Bromo-7-fluoro-1H-indole 96%
100g
$ 5994.00

Total 31 raw suppliers

Chemical Property of 5-bromo-7-fluoro-1H-indole

Chemical Property:

Vapor Pressure:0.000829mmHg at 25°C
Melting Point:28-32°C
Boiling Point:315.1°C at 760 mmHg
PKA:14.58±0.30(Predicted)
Flash Point:144.3°C
PSA：15.79000
Density:1.75g/cm³
LogP:3.06950
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:212.95894
Heavy Atom Count:11
Complexity:153

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-7-fluoro-1H-indole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-37/38-41
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC2=C(C=C(C=C21)Br)F

Technology Process of 5-bromo-7-fluoro-1H-indole

There total 1 articles about 5-bromo-7-fluoro-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 321-23-3
4-bromo-2-fluoronitrobenzene

: 1826-67-1
vinyl magnesium bromide

: 883500-73-0
5-bromo-7-fluoro-1H-indole

Guidance literature:: In tetrahydrofuran; at -40 ℃;
DOI:10.1002/ejoc.200600118

Reference yield: 58.0%

: 883500-73-0
5-bromo-7-fluoro-1H-indole

: 124-38-9,18923-20-1
carbon dioxide

: 256935-99-6
7-fluoroindole-5-carboxylic acid

Guidance literature:: 5-bromo-7-fluoro-1H-indole; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃;

carbon dioxide; In tetrahydrofuran; hexane; cooling;
DOI:10.1002/ejoc.200600118

Reference yield: 43.0%

: 883500-73-0
5-bromo-7-fluoro-1H-indole

: 98-09-9
benzenesulfonyl chloride

: 1401727-07-8
1-benzenesulfonyl-5-bromo-7-fluoro-1H-indole

Guidance literature:: 5-bromo-7-fluoro-1H-indole; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.166667h;

benzenesulfonyl chloride; In tetrahydrofuran; at 20 ℃; for 2h;