TF-BF

Base Information

Chemical Name:TF-BF
CAS No.:209861-00-7
Molecular Formula:C24H22F2O5
Molecular Weight:428.432
Hs Code.:
Mol file:209861-00-7.mol

Synonyms:(1S,5R,6R,7R)-2-oxa-7-benzoyloxy-6-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl]bicyclo[3.3.0]octan-3-one;(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate;

Suppliers and Price of TF-BF

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate 95+%
250mg
$ 742.00

Matrix Scientific
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate 95+%
1g
$ 1647.00

Crysdot
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-ylbenzoate 95+%
1g
$ 550.00

Chemenu
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-ylbenzoate 95%
1g
$ 514.00

American Custom Chemicals Corporation
(3AR,4R,5R,6AS)-4-((E)-3,3-DIFLUORO-4-PHENOXYBUT-1-EN-1-YL)-2-OXOHEXAHYDRO-2H-CYCLOPENTA[B]FURAN-5-YL BENZOATE 95.00%
1G
$ 1575.00

American Custom Chemicals Corporation
(3AR,4R,5R,6AS)-4-((E)-3,3-DIFLUORO-4-PHENOXYBUT-1-EN-1-YL)-2-OXOHEXAHYDRO-2H-CYCLOPENTA[B]FURAN-5-YL BENZOATE 95.00%
5MG
$ 505.38

Alichem
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-ylbenzoate
1g
$ 544.50

AK Scientific
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-ylbenzoate
1g
$ 2273.00

AK Scientific
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-ylbenzoate
250mg
$ 1051.00

Aaron Chemicals
2H-Cyclopenta[b]furan-2-one,5-(benzoyloxy)-4-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-,(3aR,4R,5R,6aS)- 95%
1g
$ 672.00

Total 47 raw suppliers

Chemical Property of TF-BF

Chemical Property:

Boiling Point:588.3±50.0 °C(Predicted)
PSA：61.83000
Density:1.31±0.1 g/cm3(Predicted)
LogP:4.43410
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TF-BF

There total 5 articles about TF-BF which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 51638-91-6
(3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate

: 209861-00-7
(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybutan-1-en-1-yl)-hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at 0 - 35 ℃; for 24h; Time; Inert atmosphere;

Reference yield:

: (2,2-difluoro-3-phenoxypropyl) dimethyl phosphate

: 39746-01-5
(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one

: 209861-00-7
(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybutan-1-en-1-yl)-hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate

Guidance literature:: (2,2-difluoro-3-phenoxypropyl) dimethyl phosphate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 30 ℃; for 0.25h; Inert atmosphere; Cooling with ice;

(1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one; In tetrahydrofuran; mineral oil; at 40 ℃; for 2h;

Reference yield:

: 237386-02-6
1-bromo-3-phenoxy-propan-2-one

: 209861-00-7
(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybutan-1-en-1-yl)-hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: (bis-(2-methoxyethyl)amino)sulfur trufluoride / dichloromethane / 6 h / 0 - 50 °C / Cooling with ice

2.1: potassium iodide / acetone; acetonitrile / 14.5 h / 20 °C / Inert atmosphere

3.1: sodium hydride / mineral oil; tetrahydrofuran / 0.25 h / 0 - 30 °C / Inert atmosphere; Cooling with ice

3.2: 2 h / 40 °C

With sodium hydride; potassium iodide; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In tetrahydrofuran; dichloromethane; acetone; acetonitrile; mineral oil;