TF-HF

Base Information

Chemical Name:TF-HF
CAS No.:209861-01-8
Molecular Formula:C17H18F2O4
Molecular Weight:324.324
Hs Code.:
Mol file:209861-01-8.mol

Synonyms:(1S,5R,6R,7R)-2-oxa-7-hydroxy-6-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl]bicyclo[3.3.0]octan-3-one;(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one;

Suppliers and Price of TF-HF

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95+%
250mg
$ 742.00

Matrix Scientific
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95+%
1g
$ 1647.00

Crysdot
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95+%
1g
$ 772.00

Crysdot
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95+%
5g
$ 2317.00

Crysdot
(3aR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95+%
250mg
$ 309.00

Chemenu
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95%
1g
$ 729.00

Chemenu
(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95%
5g
$ 2188.00

Biosynth Carbosynth
(3aR,4R,5R,6aS)-4-[(1E)-3,3-Difluoro-4-phenoxy-1-butenyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one
25 mg
$ 101.75

Biosynth Carbosynth
(3aR,4R,5R,6aS)-4-[(1E)-3,3-Difluoro-4-phenoxy-1-butenyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one
250 mg
$ 462.50

Biosynth Carbosynth
(3aR,4R,5R,6aS)-4-[(1E)-3,3-Difluoro-4-phenoxy-1-butenyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one
50 mg
$ 156.50

Total 41 raw suppliers

Chemical Property of TF-HF

Chemical Property:

Boiling Point:484.2±45.0 °C(Predicted)
PKA:14.19±0.40(Predicted)
PSA：55.76000
Density:1.355±0.06 g/cm3(Predicted)
LogP:2.56940
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(3AR,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TF-HF

There total 25 articles about TF-HF which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: C₃₀H₂₆F₂O₅

: 209861-01-8
(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one

Guidance literature:: C₃₀H₂₆F₂O₅; With potassium carbonate; In methanol; at 20 ℃; for 2h;

With hydrogenchloride; In methanol; water; at 0 ℃; for 1h; Solvent; Acidic conditions;

Reference yield: 79.0%

: (3aR,4R,5S,6R,6aR)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxy-6-iodohexahydro-2H-cyclopenta[b]furan-2-one

: 209861-01-8
(3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃; for 1h;
DOI:10.1021/acs.orglett.0c00745