7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carbaldehyde

Base Information

• Chemical Name: 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carbaldehyde
• CAS No.: 944940-91-4
• Molecular Formula: C28H23NO
• Molecular Weight: 389.497
• Mol file: 944940-91-4.mol

Synonyms:7-(diphenylaMino)-9,9-diMethyl-9H-fluorene-2-carbaldehyde;7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carboxaldehyde

Chemical Property of 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carbaldehyde

Chemical Property:

• PSA: 20.31000
• LogP: 7.27520

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carbaldehyde

There total 7 articles about 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C28H25NO → 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carboxaldehyde (944940-91-4)

Guidance literature:

With manganese(IV) oxide; In toluene; Reflux;

Reference yield: 93.0%

2-bromo-7-N,N’-diphenylamino-9,9’-dimethyl-9H-fluorene (302579-16-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carboxaldehyde (944940-91-4)

Guidance literature:

2-bromo-7-N,N’-diphenylamino-9,9’-dimethyl-9H-fluorene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; at -78 - 0 ℃; for 1.5h;

DOI:10.1039/c6ob00379f

Reference yield: 67.0%

7-bromo-9,9-dimethyl-9H-fluorene-2-carbaldehyde (944940-90-3) + diphenylamine (122-39-4) → 7-(diphenylamino)-9,9-dimethyl-9H-fluorene-2-carboxaldehyde (944940-91-4)

Guidance literature:

With tri-tert-butyl phosphine; palladium diacetate; caesium carbonate; In toluene; for 24.5h; Inert atmosphere; Reflux;

DOI:10.1021/ja4004393

upstream raw materials:

2,7-dibromo-9,9-dimethyl-9H-fluorene

7-bromo-9,9-dimethyl-9H-fluorene-2-carbaldehyde

diphenylamine

2-bromo-7-N,N’-diphenylamino-9,9’-dimethyl-9H-fluorene

Downstream raw materials:

5-(2-(7-(diphenylamino)-9,9-dimethyl-fluoren-2-yl)benzothiazol-6-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(7-(diphenylamino)-9,9-dimethyl-9H-fluoren-2-yl)benzo[d]thiazol-6-yl)tetrahydrofuran-3-ol

7-(6-bromobenzothiazol-2-yl)-9,9-dimethyl-N,N-diphenyl-fluoren-2-amine