(S)-3-AMINO-3-(PYRIDIN-4-YL)PROPANOIC ACID

Base Information

• Chemical Name: (S)-3-AMINO-3-(PYRIDIN-4-YL)PROPANOIC ACID
• CAS No.: 444806-04-6
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.18
• Mol file: 444806-04-6.mol

Synonyms:(S)-3-AMINO-3-(PYRIDIN-4-YL)PROPANOIC ACID;(S)-3-AMINO-3-PYRIDIN-4-YL-PROPIONIC ACID

Chemical Property of (S)-3-AMINO-3-(PYRIDIN-4-YL)PROPANOIC ACID

Chemical Property:

• PSA: 76.21000
• LogP: 1.25640

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-3-Amino-3-(pyridin-4-yl)propanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-3-Amino-3-(pyridin-4-yl)propanoicacid is used in the enzymic enantioselective synthesis of β-aryl- and β-heteroaryl-substituted β-amino acids via lipase-catalyzed β-amino ester hydrolysis.

Technology Process of (S)-3-AMINO-3-(PYRIDIN-4-YL)PROPANOIC ACID

There total 1 articles about (S)-3-AMINO-3-(PYRIDIN-4-YL)PROPANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(±)-ethyl 3-amino-3-(pyridin-4-yl)propanoate (77742-28-0) → (S)-3-amino-3-(4-pyridyl)propanoic acid (444806-04-6) + ethyl (R)-3-amino-3-(4-pyridyl)propanoate (1213912-39-0)

Guidance literature:

With water; In di-isopropyl ether; at 25 ℃; for 24h; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tetasy.2009.06.019

upstream raw materials:

(±)-ethyl 3-amino-3-(pyridin-4-yl)propanoate